Molecular Biomarkers in Inflammatory Disease
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 30 May 2025 | Viewed by 569
Special Issue Editor
Interests: western blot; inflammation; flow cytometry; innate immunity; cell culture; immunity; cancer biology; immunohistochemistry; immunofluorescence; cellular immunology
Special Issue Information
Dear Colleagues,
Inflammatory diseases, such as autoimmune disorders, inflammatory bowel disease, and sepsis, are driven by dysregulated immune responses and chronic inflammation. Molecular biomarkers play a pivotal role in enhancing our understanding of these conditions, allowing for earlier diagnosis, personalized treatment, and better outcome prediction. This Special Issue in Life invites original research, reviews, and clinical studies on the discovery, validation, and clinical application of molecular biomarkers in inflammatory diseases, with a focus on the pharmacological aspects.
In addition to identifying novel biomarkers for early detection and prognosis, the Issue will explore biomarkers predictive of therapeutic responses and drug efficacy. The role of genetic, epigenetic, and transcriptomic markers in defining disease subtypes and pharmacogenomic insights into how individual genetic variations affect drug response are also of interest. Contributions utilizing omics technologies and bioinformatics to uncover molecular signatures that inform pharmacological interventions are encouraged.
This Special Issue aims to integrate biomarker discovery with pharmacological research to enhance therapeutic precision and improve clinical outcomes in inflammatory diseases. Contributions from both preclinical and human studies are welcome.
Dr. Stelvio Tonello
Guest Editor
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Keywords
- cytokines, chemokines, and immune mediators as pharmacodynamic biomarkers
- genomic and epigenomic contributions to drug response variability
- proteomic and metabolomic profiling to guide pharmacotherapy in inflammation
- biomarker-driven strategies for drug development and personalized treatment
- mechanistic studies on drug–biomarker interactions and their clinical relevance
- novel biomarkers for predicting adverse drug reactions in inflammatory diseases
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