Prevention, Diagnosis, and Treatment of Gestational Diseases

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 629

Special Issue Editor


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Guest Editor
Department of Obstetrics and Gynecology, University of Szeged, H-6725 Szeged, Hungary
Interests: perinatal ultrasound; serum markers for complications of pregnancy; histopathology of the placenta; neonatal pathological conditions
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Special Issue Information

Dear Colleagues,

Gestational diseases are health conditions that arise during pregnancy, affecting both mother and fetus. Effective prevention, early diagnosis, and proper treatment are crucial to ensure maternal and fetal well-being. Prevention involves maintaining a healthy lifestyle before and during pregnancy. Regular prenatal care, balanced nutrition, exercise, and avoiding harmful substances like tobacco, alcohol, and certain medications can significantly reduce the risk of gestational diseases. Genetic counseling and preconception check-ups are also helpful for women with a family history of certain conditions.

The diagnosis of gestational diseases typically involves routine prenatal screenings and medical evaluations. Common diagnostic tools include blood tests, ultrasounds, glucose tolerance tests, and urine analysis. Regular check-ups help to detect conditions such as gestational diabetes, preeclampsia, and infections. Early diagnosis allows healthcare providers to manage these conditions before they cause complications. Treatments for gestational diseases vary depending on the condition. Gestational diabetes is often managed through diet, exercise, and insulin, if necessary. Preeclampsia may require medications to lower blood pressure, as well as bed rest. Infections are treated with the appropriate antibiotics. In severe cases, hospitalization may be necessary to ensure the safety of both mother and baby. Comprehensive prenatal care, combined with early diagnosis and timely treatment, plays a vital role in preventing and managing gestational diseases. By addressing these health issues proactively, the risk of complications can be minimized, promoting healthier pregnancy outcomes for both mother and child.

Dr. Andrea Suranyi
Guest Editor

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Keywords

  • gestational diseases
  • gestational diabetes
  • preeclampsia
  • pregnancy complications

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Published Papers (2 papers)

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7 pages, 855 KiB  
Case Report
Diagnosis and Management of Struma Ovarii in Pregnancy: A Case Report
by Isidoro Narbona Arias, Lucia Castaño Frías, María Marfil Gonzalez, Laura Baños Cárdenas and Jesús S. Jimenez Lopez
Life 2025, 15(8), 1328; https://doi.org/10.3390/life15081328 - 21 Aug 2025
Abstract
Adnexal tumors during pregnancy are rare, with a prevalence ranging from 0.05% to 3%, and in most cases, they are benign. Struma ovarii, a monodermal teratoma, consists of over 50% thyroid tissue and accounts for 2.7% of ovarian teratomas. It typically affects women [...] Read more.
Adnexal tumors during pregnancy are rare, with a prevalence ranging from 0.05% to 3%, and in most cases, they are benign. Struma ovarii, a monodermal teratoma, consists of over 50% thyroid tissue and accounts for 2.7% of ovarian teratomas. It typically affects women aged 40–60 and is exceptionally rare during pregnancy. Diagnosis is often only established after surgical intervention and histological examination. We present the case of a 39-year-old pregnant woman (gravida 2, para 1) at 19 weeks of gestation who presented with acute lower abdominal pain. At her first visit at 11 weeks, ultrasound revealed a 12 cm multilocular left adnexal mass. Initial conservative management was followed by emergency laparoscopy due to suspected ovarian torsion, resulting in a left oophorectomy. Histopathology confirmed struma ovarii. Thyroid function tests (TSH, FT4) remained within normal limits throughout pregnancy. The pregnancy continued without further complications, culminating in a spontaneous vaginal delivery at 40 + 4 weeks of a healthy female infant weighing 3800 g. Due to the rarity of this condition, treatment guidelines remain undefined, with management decisions relying on limited case reports and clinical judgment. This report highlights the importance of detailed evaluation and individualized management in such uncommon presentations during pregnancy. Full article
(This article belongs to the Special Issue Prevention, Diagnosis, and Treatment of Gestational Diseases)
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10 pages, 223 KiB  
Case Report
Total Intravenous Anesthesia Using Target-Controlled Infusion with Propofol for Category 1 Emergency Cesarean Section in Patients with Preeclampsia with Severe Features
by Janos Szederjesi, Emoke Almasy, Oana Elena Branea and Matild Keresztes
Life 2025, 15(8), 1237; https://doi.org/10.3390/life15081237 - 4 Aug 2025
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Abstract
Preeclampsia with severe features presents major anesthetic challenges, particularly in category 1 cesarean sections, in which rapid, safe, and hemodynamically stable induction is critical. Neuraxial techniques may be controversial due to neurological symptoms, making general anesthesia a viable option. However, traditional general anesthesia [...] Read more.
Preeclampsia with severe features presents major anesthetic challenges, particularly in category 1 cesarean sections, in which rapid, safe, and hemodynamically stable induction is critical. Neuraxial techniques may be controversial due to neurological symptoms, making general anesthesia a viable option. However, traditional general anesthesia may exacerbate hypertension and increase maternal and fetal risks. Two primigravida patients with elevated blood pressure and neurological symptoms underwent category 1 cesarean delivery under TIVA-TCI with propofol, using the Marsh model. Hemodynamic stability, drug dosing, and maternal–neonatal outcomes were monitored. Sufentanil was administered for analgesia; neuromuscular blockade was achieved with rocuronium and reversed with sugammadex. No BIS or TOF monitoring was available. Both patients maintained stable hemodynamics and oxygenation throughout surgery. Intubation was successfully performed at an effect-site concentration of 3.5 µg/mL. Neonatal Apgar scores were within acceptable limits. No major complications occurred intraoperatively or postoperatively. TCI allowed individualized dosing and smooth emergence. TIVA-TCI with propofol appears to be a viable alternative to volatile-based general anesthesia in category 1 emergencies for cesarean sections for patients with preeclampsia with severe features, especially when neuraxial anesthesia is controversial. It offers hemodynamic stability and controlled depth of anesthesia, though its use requires experience and may not be optimal in cases requiring ultra-rapid induction. Full article
(This article belongs to the Special Issue Prevention, Diagnosis, and Treatment of Gestational Diseases)
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