Human Infertility and Reproductive Endocrinology: 2nd Edition

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Reproductive and Developmental Biology".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 488

Special Issue Editor


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Guest Editor
Unit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, Padova, Italy.
Interests: reproductive endocrinology; male infertility; andrology; hypogonadism; proteomics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The second volume of this Special Issue follows on from the success of the first. We invite you to publish your research in this edition of “Human Infertility and Reproductive Endocrinology” (https://www.mdpi.com/journal/life/special_issues/6R8KIXVW2L).

Infertility is a common clinical problem, affecting 13% to 15% of couples worldwide. In addition, infertility is considered a public problem, not only affecting couples’ lives, but also healthcare services and the social environment. The male factor is solely responsible for about 20% of infertile couples and contributory to another 30–40%. The female factor is responsible, solely or associated with the male factor, for about 50% of the cases.

This Special Issue will focus on human fertility and infertility, both at the molecular and clinical levels, including the hormonal regulation of male and female fertility, diagnosis and treatment of diseases causing infertility, and the clinical management of infertile couples.

Dr. Giuseppe Grande
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • infertility
  • reproduction
  • reproductive endocrinology
  • male infertility
  • female infertility

Published Papers (1 paper)

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Research

13 pages, 255 KiB  
Article
Retrospective Analysis of Effective Management Strategies for Primary Amenorrhea of Reproductive Age in Saudi Arabia
by Hanadi Bakhsh
Life 2024, 14(6), 772; https://doi.org/10.3390/life14060772 - 17 Jun 2024
Viewed by 334
Abstract
Primary amenorrhea, the absence of menstruation by age 15, can have significant implications for reproductive health and overall well-being. This retrospective study aimed to evaluate the effectiveness of various management strategies for primary amenorrhea among women of reproductive age in Saudi Arabia. Medical [...] Read more.
Primary amenorrhea, the absence of menstruation by age 15, can have significant implications for reproductive health and overall well-being. This retrospective study aimed to evaluate the effectiveness of various management strategies for primary amenorrhea among women of reproductive age in Saudi Arabia. Medical records of 63 eligible patients from 2018 to 2023 were analyzed, assessing diagnostic methods, treatment modalities, and associated outcomes. The findings revealed that hormonal therapy was the most commonly employed management strategy (50.0%) and demonstrated the highest rate of achieving menstrual regularity (62.5%). Surgical interventions were utilized in 28.1% of cases, with a 50.0% rate of symptom resolution. Lifestyle modifications were less frequent (21.9%) but showed a moderate rate of symptom resolution (35.7%). Logistic regression analysis identified age, underlying etiology, and management strategy as significant predictors of treatment success. Subgroup analyses highlighted the efficacy of hormonal therapy and lifestyle modifications for genetic etiologies, while surgical interventions were more effective for anatomical causes. The study underscores the importance of a comprehensive diagnostic approach and personalized treatment plans tailored to individual patient characteristics. Despite limitations, the findings contribute to the understanding of optimal management strategies for primary amenorrhea and emphasize the need for multidisciplinary collaboration in addressing this complex condition. Full article
(This article belongs to the Special Issue Human Infertility and Reproductive Endocrinology: 2nd Edition)
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