Diabetic Liver Disease
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: closed (20 August 2020)
Special Issue Editor
2. Japan Strategic Medical Administration Research Center (J-SMARC), Nagoya, Aichi, Japan
Interests: nonalcoholic steatohepatitis; oxidative stress; hepatic fibrosis; diabetes mellitus; liver cirrhosis; hepatocellular carcinoma
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Nonalcoholic fatty liver disease (NAFLD) which is the most prevalent chronic liver disease, is associated with type 2 diabetes (T2D). Nonalcoholic steatohepatitis (NASH), a severe form of NAFLD, can progress to cirrhosis, hepatocellular carcinoma (HCC), and hepatic failure. Liver-related mortality is the 3rd leading cause in T2D patients. NASH can be called “diabetic liver disease (DLD)”. Accumulating evidence shows that PNPLA3 SNP is associated with fibrosis progression or HCC development. This Special Issue will include papers investigating the pathological mechanisms of T2DM and liver diseases such as NASH, and diagnostics using new biomarkers. Furthermore, experimental in vitro and in vivo studies and clinical studies examining potential new approaches to attenuate DLD are welcome. The journals IJMS and Life will jointly be publishing a Special Issue covering the topic “Diabetic Liver Disease”. This Special Issue welcomes original research and review papers.
Suggested Topics:
- Mechanisms of insulin resistance and hepatic steatosis/fibrosis;
- The role of SNPs with disease severity in DLD;
- The role of microbiota in DLD;
- Endocrine system in DLD;
- Antifibrotic agents in DLD;
- How can we stop HCC development?
- Mechanisms of cardiac/renal disease and DLD;
- Mechanisms of extrahepatic neoplasms development in DLD;
- Novel antidiabetic drugs in DLD;
- Noninvasive tests (NITs) of hepatic fibrosis in DLD.
Assoc. Prof. Dr. Yoshio Sumida
Guest Editor
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Keywords
- Nonalcoholic fatty liver disease
- Hepatocellular carcinoma
- Nonalcoholic steatohepatitis
- Type 2 diabetes
- Hepatic fibrosis
- Liver cirrhosis
- PNPLA3
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