Applications of Dermatoscopy in Skin Diseases: 2nd Edition

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 522

Special Issue Editors


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Guest Editor
Centrum Medyczne Zwierzyniecka, Poznań, Poland
Interests: skin cancer; melanoma; inflammoscopy; autoimmunity; artificial intelligence; total body photography and ultraviolet reflectance dermatoscopy; polarization
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Institute of Dermatology, “Santa Maria della Misericordia” University Hospital, Udine, Italy
Interests: dermoscopy; immune-mediated skin diseases; inflammoscopy; pediatric dermatology; psoriasis; rare diseases; skin of color; skin tumors
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Melanoma and Skin Cancer Unit, Department of Dermatology, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile
Interests: skin cancer; dermoscopy; reflectance confocal microscopy; optical coherence tomography; artificial intelligence; melanoma; Mohs micrographic surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The editors are grateful to the many researchers who contributed to the success of the first volume of this Special Issue (https://www.mdpi.com/journal/life/special_issues/Y89R1SX4Z6). We are very pleased to announce the second volume of our Special Issue, titled “Applications of Dermatoscopy in Skin Diseases: 2nd Edition”.

Dermatoscopy is an auxiliary non-invasive in vivo diagnostic method complementary to clinical examination and pathology. It enables the visualization of submacroscopic structures in the skin, mucosa, and adnexa, and has been proved to have a tremendous impact on diagnostic accuracy, decision making, and disease monitoring. In recent decades, we witnessed the rapid development of devices, including the implementation of polarized light source, multispectral illumination, optical super-high magnification dermatoscopy, and finally, the use of ultraviolet diodes. Once used as a handheld device, dematoscopes are becoming videodermatoscopes, easily attached to smartphones and cameras allowing for clinical and microscopic data storage, digital follow-up and data transfer/processing (telehealth and artificial intelligence). Even though the method was initially intended to be used in skin cancer diagnosis, its scope became very vast including non-neoplastic dermatoses, infestations and infectious diseases, abnormalities of the adnexa (hair, nails, teeth), extending to mucosal disorders, genital dermatoses, and esthetic medicine.

We would like to invite you to contribute papers addressing all the aforementioned aspects related to this Special Issue on “Applications of Dermatoscopy in Skin Diseases.”

Dr. Paweł Pietkiewicz
Dr. Enzo Errichetti
Dr. Cristian Navarrete
Guest Editors

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Keywords

  • melanoma
  • skin cancer
  • inflammoscopy
  • trichoscopy
  • ultraviolet reflectance dermatoscopy
  • skin of color
  • basal cell carcinoma
  • squamous cell carcinoma
  • nevus
  • digital dermoscopy

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Published Papers (1 paper)

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Review

17 pages, 2069 KB  
Review
Dermoscopy of Acquired Perforating Dermatoses: A Case Series and Review of the Literature
by Maria-Myrto Papadopoulou, Emmanouil Karampinis, Dimitrios Sgouros, Styliani Sakellaropoulou, Elizabeth Lazaridou, Aimilios Lallas and Zoe Apalla
Life 2025, 15(12), 1786; https://doi.org/10.3390/life15121786 - 21 Nov 2025
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Abstract
Acquired perforating dermatoses (APD) represent a group of papulonodular skin disorders characterized by transepidermal elimination of dermal components, most frequently arising in patients with poorly controlled chronic systemic conditions such as diabetes mellitus (DM) and chronic renal failure (CRF). The four classical subtypes [...] Read more.
Acquired perforating dermatoses (APD) represent a group of papulonodular skin disorders characterized by transepidermal elimination of dermal components, most frequently arising in patients with poorly controlled chronic systemic conditions such as diabetes mellitus (DM) and chronic renal failure (CRF). The four classical subtypes include acquired reactive perforating collagenosis (RPC), Kyrle’s disease (KD), elastosis perforans serpiginosa (EPS), and perforating folliculitis (PF). Owing to their rarity and the often-complex comorbidities of affected individuals, accurate diagnosis of APD may be challenging. In this context, dermoscopy has emerged as a valuable noninvasive tool that enhances diagnostic accuracy and supports clinical decision-making. This study aimed to characterize the dermoscopic features of APD through a case series and subsequent literature review. We present clinical and dermoscopic findings from a case series of 10 patients with APD followed by a literature review of 17 published case reports and 2 case series. The predominant dermoscopic pattern comprised a central yellow-to-brown structureless area, a surrounding white rim or a broader white structureless area with or without scaling, and an outer erythematous area containing dotted or hairpin vessels. Variations in these features appeared to reflect different stages of lesion evolution. The findings reinforce dermoscopy as a useful adjunct for the recognition, characterization, and monitoring of APD, providing additional insights into disease progression and contributing to improved diagnostic accuracy and clinical management. Full article
(This article belongs to the Special Issue Applications of Dermatoscopy in Skin Diseases: 2nd Edition)
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