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Life
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Diet and Vascular Disease
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Diet and Vascular Disease

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 25 March 2025 | Viewed by 3497

Special Issue Editors

Dr. Natale Musso

E-Mail Website
Guest Editor
Ospedale Policlinico San Martino, 16132 Genova, Italy
Interests: catecholamines; ABPM; dietary sodium; blood pressure measurement
Dr. Federico Gatto

E-Mail Website
Guest Editor
IRCCS Ospedale Policlinico San Martino, 16132, Gonova, Italy
Interests: pituitary; diabetes insipidus; SIADH; salt intake; secondary hypertension
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The dietary approach plays a primary role in vascular and heart disease. Although a reduction in dietary salt is recommended as the main approach in hypertension, kidney diseases and heart failure, much debate still exists about how low a low-sodium diet should be; in recent years a great discussion among scientists has been ignited and many papers have expressed different views. In fact, even the methods for the evaluation of sodium intake are under scrutiny. Furthermore, although table salt represents the common source of dietary sodium, confusion still exists in the literature about salt and sodium amounts, weights and roles.

Diet is a basic step in the treatment of dyslipidaemias, too, even if the pharmacological approach remains irreplaceable in cardiovascular prevention.

Additionally, in the secondary forms of hypertension, sodium has been shown to play a strong role in inducing target organ damage, such as left ventricular hypertrophy.

In this Special Issue of the journal Life, some international authors active in these research sectors will review the evidence on the role of dietary factors in the pathophysiology of the vascular diseases and in the induction of organ damage, clarifying the different views in this relevant field and contributing to this fierce debate.

Dr. Natale Musso
Dr. Federico Gatto
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular disease
  • cardiovascular risk
  • diet
  • dyslipidaemias
  • heart failure
  • human
  • hypertension
  • sodium
  • salt

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Published Papers (3 papers)

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Review

62 pages, 574 KiB  
Review
The Association between Food Groups, Nutraceuticals, and Food Supplements Consumption on Vascular Health Outcomes: A Literature Review
by Xenophon Theodoridis, Michail Chourdakis, Androniki Papaemmanouil, Stavroula Chaloulakou, Niki Papageorgiou, Athina Vasiliki Georgakou, Georgios Chatzis and Areti Triantafyllou
Life 2024, 14(9), 1210; https://doi.org/10.3390/life14091210 - 23 Sep 2024
Viewed by 282
Abstract
Vascular aging, marked by alterations in the structure and function of blood vessels, including heightened arterial stiffness and impaired endothelial function, is linked to a higher likelihood of developing cardiovascular and age-associated pathological conditions. Oxidative stress and inflammation are key stimulation factors in [...] Read more.
Vascular aging, marked by alterations in the structure and function of blood vessels, including heightened arterial stiffness and impaired endothelial function, is linked to a higher likelihood of developing cardiovascular and age-associated pathological conditions. Oxidative stress and inflammation are key stimulation factors in vascular aging. Engaging in healthy dietary habits could enhance the functioning of blood vessels. The aim of this study was to conduct a literature review of the evidence regarding the relationship between food regimens, nutraceuticals, and dietary supplements and vascular health. A search of electronic databases, including PubMed, Scopus, and Web of Science Core Collection, was performed. Experimental and observational studies evaluating the association between food groups, nutraceuticals, supplements, and endothelial function and/or arterial stiffness were deemed eligible for this narrative review. Based on the current body of the included studies, food groups, nutraceuticals, and dietary supplements may not demonstrate superiority over placebos in enhancing markers of vascular health. To obtain more reliable evidence on the effectiveness of interventions in vascular health, additional RCTs with larger sample sizes, extended follow-up periods, and multi-center participation are necessary. Enhancing the credibility of these RCTs requires better control of dietary variables and more precise measurement of vascular health markers. Full article
(This article belongs to the Special Issue Diet and Vascular Disease)
12 pages, 881 KiB  
Review
From a Cup of Tea to Cardiovascular Care: Vascular Mechanisms of Action
by Marios Sagris, Panayotis K. Vlachakis, Spyridon Simantiris, Panagiotis Theofilis, Maria Gerogianni, Paschalis Karakasis, Konstantinos Tsioufis and Dimitris Tousoulis
Life 2024, 14(9), 1168; https://doi.org/10.3390/life14091168 - 15 Sep 2024
Viewed by 465
Abstract
Tea consumption is increasingly recognized for its potential benefits to cardiovascular health. This study reviews the available research, concentrating on the major components of tea and their mechanisms of action in the cardiovascular system. Tea is abundant in bioactive compounds, such as flavonoids [...] Read more.
Tea consumption is increasingly recognized for its potential benefits to cardiovascular health. This study reviews the available research, concentrating on the major components of tea and their mechanisms of action in the cardiovascular system. Tea is abundant in bioactive compounds, such as flavonoids and polysaccharides, which possess significant antioxidant and anti-inflammatory properties. These compounds play a crucial role in mitigating oxidative stress and inflammation, thereby supporting cardiovascular health. They enhance endothelial function, leading to improved vascular relaxation and reduced arterial stiffness, and exhibit antithrombotic effects. Additionally, regular tea consumption is potentially associated with better regulation of blood pressure, improved cholesterol profiles, and effective blood sugar control. It has been suggested that incorporating tea into daily dietary habits could be a practical strategy for cardiovascular disease prevention and management. Despite the promising evidence, more rigorous clinical trials are needed to establish standardized consumption recommendations and fully understand long-term effects. This review offers a more comprehensive analysis of the current evidence based on endothelium function and identifies the gaps that future research should address. Full article
(This article belongs to the Special Issue Diet and Vascular Disease)
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24 pages, 346 KiB  
Review
The Effect of Diet on Vascular Aging: A Narrative Review of the Available Literature
by Xenophon Theodoridis, Michail Chourdakis, Androniki Papaemmanouil, Stavroula Chaloulakou, Athina Vasiliki Georgakou, Georgios Chatzis and Areti Triantafyllou
Life 2024, 14(2), 267; https://doi.org/10.3390/life14020267 - 17 Feb 2024
Cited by 1 | Viewed by 2448
Abstract
Early vascular aging is related to various cardiovascular diseases including hypertension, coronary heart disease, and stroke. Healthful lifestyle practices and interventions, including dietary regimens and consistent aerobic exercise, exert favorable modulation on these processes, thereby diminishing the risk of cardiovascular disease with advancing [...] Read more.
Early vascular aging is related to various cardiovascular diseases including hypertension, coronary heart disease, and stroke. Healthful lifestyle practices and interventions, including dietary regimens and consistent aerobic exercise, exert favorable modulation on these processes, thereby diminishing the risk of cardiovascular disease with advancing age. The principal objective of this review was to conduct a comprehensive evaluation and synthesis of the available literature regarding the effectiveness of different diets on vascular health, such as arterial stiffness and endothelial function. To conduct this review, a thorough search of electronic databases including PubMed, Scopus, and Web of Science Core Collection was carried out. Based on the existing evidence, the Mediterranean, Dietary Approaches to Stop Hypertension, and low-calorie diets may have a beneficial effect on vascular health. However, more randomized controlled trials with sufficient sample sizes, longer follow-ups, rigorous methodologies, and, possibly, head-to-head comparisons between the different diets are needed to shed light on this topic. Full article
(This article belongs to the Special Issue Diet and Vascular Disease)
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