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JPM
Special Issues
Rehabilitation for Neurological, Psychiatric and Psychological Disorders: A Current Challenge...
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Rehabilitation for Neurological, Psychiatric and Psychological Disorders: A Current Challenge to Evaluate and Treat Traditional Diseases

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 1646

Special Issue Editors

Dr. Giacomo Farì

E-Mail Website
Guest Editor
Department of Experimental Medicine (Di.Me.S.), University of Salento, 73100 Lecce, Italy
Interests: rehabilitation; sport medicine; musculoskeletal pain; osteoarthritis; paralympics
Special Issues, Collections and Topics in MDPI journals
Dr. Andrea Bernetti

E-Mail Website
Guest Editor
Department of Experimental Medicine (Di.Me.S.), University of Salento, 73100 Lecce, Italy
Interests: rehabilitation medicine; physiotherapy; COVID-19; osteoarthritis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Neurological, psychiatric and psychological diseases are becoming more and more widespread all over the world, determining difficult conditions of disability due to cognitive impairment and behavioural disorders.

This Special Issue aims to collect valuable scientific contributions to improve the evaluation and treatment of these disorders and to build new rehabilitation strategies for these patients. Therefore, any advancement for treating these patients is desirable, ranging from new evaluation tools to new and traditional drugs, and from physical activity to rehabilitative protocols. Original articles and reviews are welcome to pursue this goal.

Dr. Giacomo Farì
Dr. Andrea Bernetti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • rehabilitation
  • neurodegenerative disease
  • behavioural disorders
  • evaluation tools
  • physical activity
  • new drugs

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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8 pages, 2415 KiB  
Case Report
The Synergistic Effects of Incobotulinum Toxin and Physiotherapy in a Rare Case of Paraparesis in a 7-Year-Old Affected by Klippel–Feil Syndrome Related to an MYH3 Gene Mutation: A Case Report
by Maurizio Ranieri, Mariagrazia Riccardi, Maria Vittoria Raele, Giacomo Farì, Marisa Megna and Riccardo Marvulli
J. Pers. Med. 2024, 14(11), 1073; https://doi.org/10.3390/jpm14111073 - 24 Oct 2024
Viewed by 1200
Abstract
Background: Klippel–Feil disease is a condition characterized by a defect in the spine, consisting of the fusion or non-separation of two or more vertebrae of the cervical tract. It affects 1 in every 50,000 newborns, and the pathogenesis remains unknown to date, although [...] Read more.
Background: Klippel–Feil disease is a condition characterized by a defect in the spine, consisting of the fusion or non-separation of two or more vertebrae of the cervical tract. It affects 1 in every 50,000 newborns, and the pathogenesis remains unknown to date, although the role of certain genes that are involved in segmentation processes is being studied. A single case of a genetic Myosin Heavy Chain 3 (MYH3) mutation is described here. Affected patients are typically distinguished by a relatively short neck, which leads to limited mobility, a low hairline, and obesity; they may also experience various other health issues. The common occurrence of comorbidities further diminishes the quality of life of these young individuals. Methods: The following case report describes the synergistic effect of Incobotulinum toxin type A and physiotherapy in a 7-year-old patient with MYH3 mutation-related Klippel–Feil syndrome (KFS) complicated by bilateral paraplegia to improve the spasticity condition of the lower limbs. To assess improvements over time, the patient underwent rating scales to determine spasticity (Modified Ashworth Scale: MAS), the neck’s range of motion (ROM), and muscle tone by using MyotonPro®. Specifically, measurements were taken on the day of the first medical examination (T0), the month after the injection and the startup of therapeutic exercise (T1), at three months (T2), and then once a month for a total of 6 months (T3, T4, and T5). Results: This therapeutic approach resulted in highly satisfactory outcomes for the child’s well-being, which was maintained until the sixth month and was accompanied by a complete absence of any side effects. Full article
(This article belongs to the Special Issue Rehabilitation for Neurological, Psychiatric and Psychological Disorders: A Current Challenge to Evaluate and Treat Traditional Diseases)
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