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Updates and Challenges in Endoscopic and Laparoscopic Surgery
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Updates and Challenges in Endoscopic and Laparoscopic Surgery

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".

Deadline for manuscript submissions: closed (31 July 2025) | Viewed by 7821

Special Issue Editor

Dr. Gabriella Teresa Capolupo

E-Mail Website
Guest Editor
Colorectal Surgery Unit, Campus Bio Medico University of Rome, Via Alvaro del Portillo 21, 00128 Roma, Italy
Interests: colorectal surgery; minimally invasive surgery; colorectal cancer; laparoscopic surgery; robotic surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

With the spread of endoscopic and laparoscopic techniques, minimally invasive surgical approaches have completely changed the field of surgery. This Special Issue examines surgical procedures, cutting-edge techniques, and clinical results, with an emphasis on the most recent research and technical developments in these fields. It seeks to address the challenges faced by surgeons and offer insightful information on the changing field of minimally invasive surgery.

Endoscopic full-thickness resection (EFTR) has become a feasible method for treating gastrointestinal tract (GIT) mucosal and sub-epithelial lesions that are resistant to traditional treatment modalities.

Therefore, although laparoscopic and endoscopic procedures have revolutionized the surgical field, persistent issues still require attention to improve surgical outcomes and patient care.

Dr. Gabriella Teresa Capolupo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gastrointestinal surgery
  • minimally invasive surgery
  • endoscopic surgery
  • endoscopic full-thickness resection
  • natural orifice surgery
  • artificial intelligence

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Published Papers (3 papers)

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Research

11 pages, 1140 KB  
Article
Tailoring the Management of Colonic Lipomas: A 10-Year Experience of Surgical and Endoscopic Resection
by Vincenzo Schiavone, Filippo Carannante, Gennaro Melone, Valentina Miacci, Gianluca Costa, Chiara Taffon, Marco Caricato, Gabriella Teresa Capolupo and Gianluca Mascianà
J. Pers. Med. 2025, 15(11), 544; https://doi.org/10.3390/jpm15110544 - 8 Nov 2025
Viewed by 392
Abstract
Introduction: Colonic lipomas (CLs) are benign neoplasms originating from adipose tissue within the gastrointestinal tract. They are often asymptomatic, but in certain cases, patients may present with gastrointestinal bleeding or symptoms related to intestinal obstruction. We report the cases of 18 patients undergoing [...] Read more.
Introduction: Colonic lipomas (CLs) are benign neoplasms originating from adipose tissue within the gastrointestinal tract. They are often asymptomatic, but in certain cases, patients may present with gastrointestinal bleeding or symptoms related to intestinal obstruction. We report the cases of 18 patients undergoing both surgical and endoscopic resection of colonic lipomas. Given the variability in symptoms, lesion size, and patient demographics, the management of CLs represents a clinical scenario where treatment must be tailored to the individual, aligning with the principles of personalized medicine. This study aims to clarify the clinical and morphological factors guiding treatment selection for colonic lipomas, emphasizing a personalized approach to management. Materials and Methods: We retrospectively reviewed a prospectively collected database of 18 patients with histological diagnosis of colon lipoma after both endoscopic and surgical resection at the Campus Bio-Medico University Hospital, Rome, from 2016 to the first months of 2025. Results: The average patient age was 66 years, and the average maximum size of lipoma was 2.87 cm. The anatomical location of lipomas is very varied, ranging from the ileocecal valve to the distal sigma, and most procedures were endoscopic. Conclusions: Despite the fact that no established guidelines about the management of the CLs are reported in literature, the different approaches are related to symptomatology. Our findings try to clarify and demonstrate how the therapeutic decision, whether endoscopic or surgical, is personalized based on the patients and their clinical condition, illustrating how CL management reflects the broader framework of personalized medicine. Our work confirms that the patients most prone to intussusception phenomena are young women with large colonic lipomas. Full article
(This article belongs to the Special Issue Updates and Challenges in Endoscopic and Laparoscopic Surgery)
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13 pages, 559 KB  
Article
The Effect of Increased Intra-Abdominal Pressure on Hemodynamics in Laparoscopic Cholecystectomy—The Experience of a Single Centre
by Elena Stamate, Alin-Ionut Piraianu, Oana-Monica Duca, Oana Roxana Ciobotaru, Ana Fulga, Iuliu Fulga, Cristian Onisor, Madalina Nicoleta Matei, Alexandru-Stefan Luchian, Adrian George Dumitrascu and Octavian Catalin Ciobotaru
J. Pers. Med. 2024, 14(8), 871; https://doi.org/10.3390/jpm14080871 - 17 Aug 2024
Cited by 2 | Viewed by 5202
Abstract
Laparoscopic cholecystectomy is characterized by reduced postoperative pain, shorter hospital stays, rapid return to preoperative physical activity, and less psychological impact on the patient. During laparoscopic cholecystectomy, the intra-abdominal insufflation of carbon dioxide with secondary increase in intra-abdominal pressure can cause important hemodynamic [...] Read more.
Laparoscopic cholecystectomy is characterized by reduced postoperative pain, shorter hospital stays, rapid return to preoperative physical activity, and less psychological impact on the patient. During laparoscopic cholecystectomy, the intra-abdominal insufflation of carbon dioxide with secondary increase in intra-abdominal pressure can cause important hemodynamic consequences, like decreased cardiac output and blood pressure, as well as compensatory increase in heart rate. The purpose of this study is to evaluate changes in cardiovascular parameters during general anesthesia in patients undergoing laparoscopic cholecystectomy. Retrospective data from 342 patients with cholecystectomy for cholelithiasis performed at Railway Hospital Galati, Romania, were reviewed. All patients received the same intraoperative anesthetics. Female patients were 85.7% (n = 293). More than half of the patients, 53.51% (n = 183), were 40–59 years old, and only 16.37% (n = 56) were under 40 years old. Patients with a normal body mass index (BMI) represented 45.6% (n = 156), 33.3% (n = 114) were underweight, and 12% (n = 42) had grade 1 obesity (BMI 25–29.9 kg/m2). The minimum intraoperative blood pressure correlated with patient gender (p 0.015 < 0.005), with men having a higher blood pressure than women (p 0.006 < 0.05), and for BMI, a higher BMI was associated with elevated blood pressure (p 0.025 < 0.05). Older age correlated with an increased maximum intraoperative blood pressure (p < 0.001 < 0.05) and with maximum intraoperative heart rate (p 0.015 < 0.05). Patients undergoing laparoscopic cholecystectomy experienced significant hemodynamic changes with pneumoperitoneum, but this type of surgical intervention was safe for patients regardless of their age. Full article
(This article belongs to the Special Issue Updates and Challenges in Endoscopic and Laparoscopic Surgery)
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13 pages, 438 KB  
Article
An Institutional Shift from Routine to Selective Diversion of Low Anastomosis in Robotic TME Surgery for Rectal Cancer Patients Using the KHANS Technique: A Single-Centre Cohort Study
by Rauand Duhoky, Guglielmo Niccolò Piozzi, Marieke L. W. Rutgers, Ioannis Mykoniatis, Najaf Siddiqi, Syed Naqvi and Jim S. Khan
J. Pers. Med. 2024, 14(7), 725; https://doi.org/10.3390/jpm14070725 - 4 Jul 2024
Cited by 1 | Viewed by 1622
Abstract
(1) Background: In recent years, there has been a change in practice for diverting stomas in rectal cancer surgery, shifting from routine diverting stomas to a more selective approach. Studies suggest that the benefits of temporary ileostomies do not live up to their [...] Read more.
(1) Background: In recent years, there has been a change in practice for diverting stomas in rectal cancer surgery, shifting from routine diverting stomas to a more selective approach. Studies suggest that the benefits of temporary ileostomies do not live up to their risks, such as high-output stomas, stoma dysfunction, and reoperation. (2) Methods: All rectal cancer patients treated with a robotic resection in a single tertiary colorectal centre in the UK from 2013 to 2021 were analysed. In 2015, our unit made a shift to a more selective approach to temporary diverting ileostomies. The cohort was divided into a routine diversion group treated before 2015 and a selective diversion group treated after 2015. Both groups were analysed and compared for short-term outcomes and morbidities. (3) Results: In group A, 63/70 patients (90%) had a diverting stoma compared to 98/135 patients (72.6%) in group B (p = 0.004). There were no significant differences between the groups in anastomotic leakages (11.8% vs. 17.8%, p = 0.312) or other complications (p = 0.117). There were also no significant differences in readmission (3.8% vs. 2.6%, p = 0.312) or reoperation (3.8% vs. 2.6%, p = 1.000) after stoma closure. After 1 year, 71.6% and 71.9% (p = 1.000) of patients were stoma-free. One major reason for the delay in stoma reversal was the COVID-19 pandemic, which only occurred in group B (0% vs. 22%, p = 0.054). (4) Conclusions: A more selective approach to diverting stomas for robotic rectal cancer patients does not lead to more complications or leaks and can be considered in the treatment of rectal cancer tumours. Full article
(This article belongs to the Special Issue Updates and Challenges in Endoscopic and Laparoscopic Surgery)
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