Drosophila - A Model System for Developmental Biology

Dear Colleagues,

It has been more than one hundred years since Thomas Hunt Morgan established Drosophila as a premier organism for biological research, and still Drosophila remains one of the most commonly-used model organisms in a variety of fields. Drosophila have been used to model development and aging, disease and homeostasis, stem cells and differentiation, neurogenesis and neurodegeneration, and many, many other processes. At times, throughout its history as a model organism, Drosophila appeared to be nearing the end of its usefulness as “better” approaches emerged, and experimental limits were reached. Despite this, new methods always appeared, better approaches turned out to have their limitations, and Drosophila research persevered. The model organisms C. elegans and Drosophila remain the major sources for rapid, genetic analysis of development and its inverse, aging. With the rise of CRISPR/Cas9, and the demand for human cell based experiments, the invertebrate models are again under pressure. This Special Issue of the Journal of Developmental Biology will provide an overview of the current standing, and most importantly highlight the directions for future invertebrate research. Contributions can be reviews, as well as research papers, covering topics of model organism research.

Dr. Nick Tolwinski
Guest Editor

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