Advances in Biocomposite Materials for Regenerative Medicine and Biomedical Applications

A special issue of Journal of Composites Science (ISSN 2504-477X). This special issue belongs to the section "Biocomposites".

Deadline for manuscript submissions: 20 August 2025 | Viewed by 340

Special Issue Editor


E-Mail Website
Guest Editor
Unit of Dentistry & Oral-Maxillo-Facial Surgery, Department of Surgery, Medicine, Dentistry and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy
Interests: histology; bone; tissue regeneration; 3D printing; dentistry

Special Issue Information

Dear Colleagues,

Biocomposite materials represent a rapidly evolving field at the intersection of biomaterials science, engineering, and regenerative medicine. These materials, combining natural and synthetic components, offer unique advantages such as biocompatibility, tuneable mechanical properties, and bioactive functionalities that promote tissue regeneration.

This Special Issue aims to highlight recent advances in the design, fabrication, and application of biocomposites for biomedical and regenerative purposes. Topics of interest include, but are not limited to, scaffold-based systems for tissue engineering, injectable or granular biocomposites for minimally invasive treatments, bioactive and stimuli-responsive materials, and composite hydrogels for soft tissue regeneration. Studies on novel fabrication techniques, such as 3D printing and bioassembly, as well as in vitro and in vivo evaluations of biocomposite performance, are also welcome.

By bringing together cutting-edge research in biomaterials and regenerative medicine, this Special Issue seeks to provide a comprehensive overview of the latest developments in biocomposite materials and their translation into clinical applications. We invite contributions from multidisciplinary fields, including materials science, biomedical engineering, and clinical research, to foster collaboration and innovation in the development of next-generation biomaterials for healthcare applications.

Dr. Paolo Savadori
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Composites Science is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biocomposite materials
  • regenerative medicine
  • tissue engineering
  • bioactive scaffolds
  • injectable biomaterials
  • biomedical applications

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

15 pages, 3551 KiB  
Article
Response Surface Methodology-Based Optimization for Enhancing the Viability of Microencapsulated Lactobacillus plantarum in Composite Materials
by Rafael González-Cuello, Joaquín Hernández-Fernández and Rodrigo Ortega-Toro
J. Compos. Sci. 2025, 9(4), 189; https://doi.org/10.3390/jcs9040189 - 15 Apr 2025
Viewed by 239
Abstract
Probiotics have gained prominence and consumer appreciation due to their potential health benefits. However, maintaining their viability and stability during gastric transit remains a challenge. This study aims to enhance the viability of microencapsulated Lactobacillus plantarum in composite microcapsules exposed to simulated gastric [...] Read more.
Probiotics have gained prominence and consumer appreciation due to their potential health benefits. However, maintaining their viability and stability during gastric transit remains a challenge. This study aims to enhance the viability of microencapsulated Lactobacillus plantarum in composite microcapsules exposed to simulated gastric juice. The independent variables investigated were low-acyl gellan gum (LAG), bacterial cellulose (BC), and calcium concentrations. The microcapsules were prepared using the internal ionic gelation method. The resulting microcapsules exhibited a uniform size distribution, with a diameter of approximately between 15 to 120 μm, making them suitable for food applications. Response surface methodology (RSM) based on the Box–Behnken design was successfully employed to optimize the concentrations of LAG, BC, and calcium. Under optimal conditions—0.63% w/v LAG, 17.91% w/v BC, and 25.12 mM Ca—the highest L. plantarum viability reached 94.28% after exposure to simulated gastric juice, with an R2 value of 99.64%. These findings demonstrate the feasibility of developing multicomponent microcapsules that effectively protect probiotic bacteria against gastric fluids, offering a promising alternative for the food industry in designing probiotic-enriched food systems. Full article
Show Figures

Figure 1

Back to TopTop