Special Issue "Prevention, Diagnosis and Management of Chronic Rhinosinusitis"
Deadline for manuscript submissions: closed (31 October 2019).
Interests: sinus surgery; rhinosinusitis; skull base reconstruction; otologic surgery
Special Issues and Collections in MDPI journals
Chronic rhinosinusitis (CRS) is a frequently-encountered disease, worldwide, distressing all age groups. Its estimated incidence is 12.3% in the US, 10.9% in Europe and 13% in China. CRS is also a condition leading to a significant decrease in the quality of life of patients. Furthermore, it is documented that CRS is also an economic burden for society: The direct costs related to diagnosis and treatment are estimated to be 8.6 billion dollars, per year, in the United States, and indirect costs related to loss of productivity are also high. Lately, we have expanded our understanding of the heterogeneous nature of CRS. An impressive body of knowledge has been accumulated on the specific roles of genetic susceptibility, different viruses, fungi and bacteria, interaction between local and systemic immunity, biofilms, mucosal and bony alterations. Understanding of the pathogenesis of the disease opens the way for new treatment developments. Treatments for this disease include medical and surgical approaches. The role of “maximal medical treatment” in CRS is still to be well-defined. In spite of the tremendous advances in the understanding of the disease process and in diagnosis and treatment algorithms, still are encountered “difficult to treat” patients and recalcitrant cases. These are the reasons why this supplement is dedicated to the diagnosis, prevention and management of CRS.
Prof. Dr. Silviu Albu
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