Migraines in Childhood: Diagnosis, Treatment, and Prognosis

Dear Colleagues,

Migraines represent the most prevalent neurological disease in childhood, involving almost 10% of children and adolescents. When the frequency of the attacks increases, possibly indicating a chronic condition, migraines can severely impact on the quality of life of the young patients and their families. In spite of this heavy burden, migraines in children have been underestimated for a long time. Randomized controlled trials to evaluate the effects of medication are scarcely available for pediatric age. Therefore, children with migraines usually undergo pharmacological treatments that are merely transferred from adult patients, often without any demonstrated evidence of efficacy or safety in the youngest population. Recent studies (Power et al., 2017; Papetti et al., 2020) have even suggested that psychological mechanisms, including the placebo effect, can be more effective than medications at improving migraines in children and adolescents. This Special Issue will offer a place to publish original research, review articles, and commentaries concerning migraines, but also other primary and secondary headaches, of childhood. Studies concerning pharmacological and non-pharmacological interventions to improve the quality of life of these young patients will be particularly welcome.

Dr. Massimiliano Valeriani
Dr. Vittorio Sciruicchio
Guest Editors

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