The Role of Biomarkers in the Diagnosis and Risk Stratification of Acute Coronary Syndrome
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 3070
Special Issue Editor
Special Issue Information
Dear Colleagues,
Biomarkers are currently attracting immense interest as they not only help with diagnosis and management but also help us to understand the pathophysiology of the disease process. The use of a large number of cardiovascular biomarkers, meant to complement the use of the electrocardiogram, echocardiography, cardiac imaging, and clinical symptom assessment, has become routine in clinical diagnosis, differential diagnosis, risk stratification, and prognosis and guides the management of patients with suspected cardiovascular diseases.
There is a broad consensus that cardiac troponin and natriuretic peptides are the preferred biomarkers in clinical practice for the diagnosis of acute coronary syndrome and heart failure, respectively, while the roles and possible clinical applications of several other potential biomarkers are still under study. We still need to identify more novel biomarkers to supplement ECGs or X-rays and provide more accurate and sensitive methods for cardiovascular disease diagnosis, risk stratification, and management. Although traditional biomarkers play a central role in the diagnosis, risk stratification, and management of coronary artery disease, they are unable to detect myocardial ischemia in the absence of necrosis, hemodynamic markers of heart failure, inflammatory markers, and a novel and innovative approach of a combination of these in a multimarker strategy.
This Special Issue aims to deepen the specific role of biomarkers in the diagnosis and risk stratification of acute coronary syndrome. We cordially invite researchers involved in basic research as well as translational studies to submit their original research, systematic reviews, and short communications to this Special Issue.
Prof. Alfredo Bardaji
Guest Editor
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Keywords
- biomarkers
- acute coronary syndrome
- prognosis
- mortality
- troponin
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