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JCM
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Emerging Trends in Cervical Spine Surgery
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Emerging Trends in Cervical Spine Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 176

Special Issue Editors

Dr. Daniel Hafez

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Guest Editor
Department of Neurosurgery, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO, USA
Interests: minimally invasive spine; muscle sparing surgery; MIS-deformity; endoscopic
Dr. Rory Murphy

E-Mail Website
Guest Editor
Department of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ, USA
Interests: cervical spinal cord injury; spinal chord compression; neurosurgery
Dr. Jacob Greenberg

E-Mail Website
Guest Editor
Department of Neurosurgery, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO, USA
Interests: cervical myelopathy; degenerative lumbar disease; data informatics

Special Issue Information

Dear Colleagues,

The field of cervical spine surgery is undergoing transformative changes driven by advancements in technology and minimally invasive and endoscopic approaches, offering patients improved outcomes with reduced morbidity. 

Motion-preserving technologies, such as cervical disk arthroplasty or laminoplasty, are gaining prominence as alternatives to traditional fusion techniques, fostering discussions on long-term outcomes, indications, and patient selection. 

Additionally, innovations in imaging, navigation, robotics, and personalized surgical planning are enhancing precision and efficiency. Moreover, advanced analytics with the use of AI and machine learning, have significant potential in patient guidance and surgical decision making

This topic will focus on the latest developments in cervical spine surgery, the evolving debate between motion-preserving procedures and fusions, and the integration of novel technologies and analyses to optimize surgical planning, patient care, and recovery.

Dr. Daniel Hafez
Dr. Rory Murphy
Dr. Jacob Greenberg
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cervical disk arthroplasty
  • laminoplasty
  • hybrid fusion
  • endoscopic cervical foraminotomy
  • endoscopic cervical laminectomy
  • cervical myelopathy
  • MIS cervical spine fusion
  • robotic/navigated cervical surgery

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Published Papers (1 paper)

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14 pages, 396 KiB  
Systematic Review
Minimally Invasive Techniques in Posterior Atlanto-Axial Fixation: State of the Art and Systematic Review
by Gianpaolo Jannelli, Luca Paun, Cédric Y. Barrey, Paola Borrelli, Karl Schaller, Enrico Tessitore and Ivan Cabrilo
J. Clin. Med. 2025, 14(13), 4657; https://doi.org/10.3390/jcm14134657 - 1 Jul 2025
Abstract
Background: The atlanto-axial segment is highly mobile and, therefore, prone to instability in the setting of inflammatory disease, infection, tumor or trauma. While minimally invasive surgical (MIS) techniques have gained acceptance in the thoracolumbar spine due to their advantages over traditional approaches, their [...] Read more.
Background: The atlanto-axial segment is highly mobile and, therefore, prone to instability in the setting of inflammatory disease, infection, tumor or trauma. While minimally invasive surgical (MIS) techniques have gained acceptance in the thoracolumbar spine due to their advantages over traditional approaches, their use at the atlanto-axial segment is controversial due to the surgical risk associated with its complex anatomy. To evaluate the current evidence on MIS atlanto-axial fixation, we carried out a systematic review of the literature and compared the reported results with those of open procedures. Methods: This systematic review follows PRISMA-DTA 2020 guidelines. A comprehensive search was conducted in November 2023 across PubMed/Medline, Google Scholar and clinicaltrials.gov using specific keywords related to minimally invasive atlanto-axial fixation. Data regarding study characteristics, patient demographics, surgical techniques, and outcomes were extracted from included studies. Results: This systematic review included 13 articles reporting on the results of surgery in 305 patients, in whom a total of 683 screws were inserted through a posterior MIS approach. N = 162 screws were inserted using the Harms–Goel technique, while N = 521 were placed using the Magerl technique. N = 40 screws were inserted using navigation guidance, while N = 643 were introduced with fluoroscopy assistance. Eight screws were misplaced. A Vertebral Artery (VA) injury was reported in three patients. With a mean value of 26.2 ± 15.3 months, the rate of fusion ranged between 80% and 100%. Conclusions: This study highlights the potential of MIS for posterior atlanto-axial fixation, which was achieved using Magerl transarticular screws in a large majority of cases. Despite technical challenges, MIS approaches appear to achieve satisfactory clinical and radiological outcomes with complication rates similar to those of open techniques. Future studies may help refine the indications for MIS and identify those cases better suited for open approaches. Full article
(This article belongs to the Special Issue Emerging Trends in Cervical Spine Surgery)
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