Current Updates on the Diagnosis and Management of Immune-Mediated Neurological Disorders in Children

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Neurology & Neurodevelopmental Disorders".

Deadline for manuscript submissions: 10 January 2026 | Viewed by 43

Special Issue Editors


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Guest Editor
Neurological Department, Pendeli’s Children Hospital, Athens, Greece
Interests: neurology; pediatric neurology; neuroimmunology; demyelinating disorders

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Guest Editor
Neurological Clinic, Metropolitan General Hospital, Athens, Greece
Interests: neurology; neuroimmunology; demyelinating disorders

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Guest Editor
Director of Multiple Sclerosis & Demyelinating Diseases Unit and Immunogenetics Laboratory, 1st Department of Neurology of Medical School, National and Kapodistrian University of Athens, Aeginition University Hospital, Vas. Sofias Ave 74, 115 28 Athens, Greece
Interests: clinical immunology; immunogenetics; neurology; multiple sclerosis; demyelinating diseases; autoimmunity
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Special Issue Information

Dear Colleagues,

Immune-mediated neurological disorders in children represent a rapidly evolving field shaped by advances in neuroimmunology, imaging, genetics, and molecular diagnostics. These conditions—such as pediatric multiple sclerosis, MOG antibody-associated disease (MOGAD), neuromyelitis optica spectrum disorder (NMOSD), GFAP astrocytopathy, autoimmune encephalitides, pediatric myasthenia gravis, and interferonopathies—pose unique challenges due to their heterogeneous presentations, complex immune mechanisms, and potential for long-term developmental impact. Recent breakthroughs in biomarker identification and immunopathogenesis have facilitated earlier, more accurate diagnoses and the development of targeted, individualized therapies. As biologic treatments and precision medicine approaches become more integrated into clinical care, outcomes and quality of life for affected children continue to improve. This Special Issue brings together leading experts to present current updates, emerging treatment paradigms, and practical strategies for managing these disorders. Our aim is to provide clinicians and researchers with a comprehensive, up-to-date resource that supports optimal care in this challenging and dynamic area of pediatric neurology

Dr. Maria Gontika
Dr. Markoglou Nikolaos
Dr. Maria Anagnostouli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neuroimmunology
  • pediatrics
  • biomarkers
  • precision medicine
  • personalized treatment

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Published Papers

This special issue is now open for submission.
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