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Clinical Advances in Head and Neck Cancer Surgery
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Clinical Advances in Head and Neck Cancer Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 2759

Special Issue Editor

Prof. Dr. Benedikt Hofauer

E-Mail Website1 Website2
Guest Editor
Department of Otorhinolaryngology, Medical University of Innsbruck, 6020 Innsbruck, Austria
Interests: head and neck surgery; treatment; imaging; diagnosis; tumors; ultrasonography; otorhinolaryngology

Special Issue Information

Dear Colleagues,

This Special Issue, “Clinical Advances in Head and Neck Cancer Surgery”, highlights the latest developments in the field of head and neck cancer surgery.

Surgical treatment is a common option for head and neck cancer. The extent of surgery depends on the stage and location of the cancer. The goal of surgery is to remove cancerous tissue alongside a margin of healthy tissue to reduce the risk of recurrence. Surgery may be performed alone or in combination with other treatments, such as radiation therapy or chemotherapy. In some cases, reconstructive surgery may be required to restore the function of the upper airway and digestive tract.

This Special Issue features articles on various topics, including surgical techniques, outcomes, and advancements in technology, providing valuable insights into the challenges and opportunities in head and neck cancer surgery in addition to offering practical guidance for clinicians for improving the care of patients with this challenging disease.

Prof. Dr. Benedikt Hofauer
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck cancer
  • surgery
  • minimally invasive surgery
  • reconstruction
  • outcomes
  • technology
  • clinical advancements
  • patient care

Published Papers (3 papers)

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Research

12 pages, 3967 KiB  
Article
The Value of the Endoscope-Holding Arm in Transoral Pharyngeal Surgery
by Aris I. Giotakis, Evangelos I. Giotakis and Efthymios Kyrodimos
J. Clin. Med. 2024, 13(2), 507; https://doi.org/10.3390/jcm13020507 - 16 Jan 2024
Viewed by 658
Abstract
Background: Transoral pharyngeal surgery is mainly feasible with the use of a microscope or robotic systems. Data about alternative methods, with lower costs and easier availability, are sparse. We intended to examine to what extent the endoscope-holding arm is a suitable alternative to [...] Read more.
Background: Transoral pharyngeal surgery is mainly feasible with the use of a microscope or robotic systems. Data about alternative methods, with lower costs and easier availability, are sparse. We intended to examine to what extent the endoscope-holding arm is a suitable alternative to the microscope or robotic systems. Material and Methods: We retrospectively reviewed subjects who underwent pharyngeal tumor resection with the endoscope-holding arm in our university department. Results: We identified 13 subjects who underwent transoral pharyngeal surgery between November 2020 and November 2023. Most subjects presented with an oropharyngeal tumor (6/11 in the lateral wall or tonsil; 4/11 in the tongue base). The oropharyngeal lateral wall or tonsillar tumors were exposed with a standard mouth gag. The tongue-base tumors or hypopharyngeal tumors were exposed with an operating laryngoscope. Advantages over the microscope included an angled view. Advantages over robotic systems included haptic feedback and a faster setup. Advantages over both the microscope and robotic systems included lower costs and easier availability. Visualization with the endoscope was sufficient and similar to that of the microscope. Bimanual action was possible with surgical forceps and a monopolar electrode. Conclusions: Transoral pharyngeal surgery was feasible with the endoscope-holding arm. The endoscope-holding arm could be a cost-efficient alternative to the microscope or robotic systems. Full article
(This article belongs to the Special Issue Clinical Advances in Head and Neck Cancer Surgery)
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8 pages, 516 KiB  
Article
The Localisation of a Tracheoesophageal Shunt during Laryn(-gopharyn)gectomy Determines the Risk of Shunt Insufficiency
by Felix Johnson and Andreas Knopf
J. Clin. Med. 2023, 12(24), 7628; https://doi.org/10.3390/jcm12247628 - 11 Dec 2023
Viewed by 795
Abstract
Background: Tracheoesophageal shunt insufficiency (TESI) is a common and potentially life-threatening complication after laryn(-gopharyn)gectomy (L(P)E). We investigated whether TESI could be the result of a specific shunt location. Methods: A monocentric, retrospective cohort analysis of 171 consecutively treated L(P)E patients was performed. Patients [...] Read more.
Background: Tracheoesophageal shunt insufficiency (TESI) is a common and potentially life-threatening complication after laryn(-gopharyn)gectomy (L(P)E). We investigated whether TESI could be the result of a specific shunt location. Methods: A monocentric, retrospective cohort analysis of 171 consecutively treated L(P)E patients was performed. Patients with a secondary prosthesis instillation and patients with insufficient postoperative imaging were excluded. Disease related data as well as location of primary voice prosthesis were assessed. Results: The cohort was divided into 62 TESI-positive and 109 TESI-negative individuals. The mean time from surgery to TESI was 32 months. No differences were observed in gender, age, tumor localization, T/R/M-status. Surgery without adjuvant therapy was more often performed in TESI-negative individuals when compared with their positive counterparts. However, Cox regression including T/N status, therapy and categorized distance of the tracheoesophageal shunt to the manubrium (≤1.5 cm vs. >1.5 cm) revealed that a distance of ≤1.5 cm was associated with a 2.1-fold increased risk of TESI, while all other parameters did not influence the event-free survival. Conclusions: Primary shunt positioning ≤1.5 cm to the ridge of the manubrium is associated with an increased risk of TESI. In these individuals secondary shunt operation resulting in a position >1.5 cm distant to the manubrium should be recommended. Full article
(This article belongs to the Special Issue Clinical Advances in Head and Neck Cancer Surgery)
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12 pages, 2283 KiB  
Article
Hemoglobin–Albumin–Lymphocyte–Platelet (HALP) Score as a Predictive Model for the Success of Reconstruction of Head and Neck Defects with Free Microvascular Flaps
by Marko Tarle, Igor Čvrljević, Marina Raguž and Ivica Lukšić
J. Clin. Med. 2023, 12(16), 5314; https://doi.org/10.3390/jcm12165314 - 15 Aug 2023
Cited by 2 | Viewed by 1017
Abstract
Significant advances in reconstructive head and neck surgery with free microvascular flaps have had a positive impact on esthetic outcomes and quality of life. However, complications still occur in some patients. This study investigated the influence of the Hemoglobin, Albumin, Lymphocyte, and Platelet [...] Read more.
Significant advances in reconstructive head and neck surgery with free microvascular flaps have had a positive impact on esthetic outcomes and quality of life. However, complications still occur in some patients. This study investigated the influence of the Hemoglobin, Albumin, Lymphocyte, and Platelet Score (HALP score), an immunonutritive marker, on complications and flap success. The retrospective analysis included 194 patients who underwent reconstruction of head and neck defects with free microvascular flaps. The HALP score correlated strongly with overall complications, including flap necrosis, infection, fistula, and hematoma. Hemoglobin, albumin, lymphocytes, and platelets individually showed associations with specific complications. HALP score was an extremely strong predictor of complications (AUC = 0.85). HALP score may be valuable for assessing patient status and predicting complications in microvascular free-flap reconstruction to allow timely interventions and improve outcomes. Further research is needed to investigate additional predictors and improve postoperative care. Full article
(This article belongs to the Special Issue Clinical Advances in Head and Neck Cancer Surgery)
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