Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.7
3.0
Journals
JCM
Special Issues
Cardiac Ablation: Current Status and Future Perspectives
jcm-logo
Submit to JCM Review for JCM Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Cardiac Ablation: Current Status and Future Perspectives

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (20 March 2025) | Viewed by 3501

Special Issue Editors

Dr. Fabrizio Guarracini

E-Mail Website
Guest Editor
Electrophysiology Unit, Cardio-Thoraco-Vascular Department, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
Interests: atrial fibrillation ablation; ventricular tachycardia ablation; supraventricular tachycardia ablation; left atrial appendage closure; ICD/PM implantation; cardiac leads extraction
Special Issues, Collections and Topics in MDPI journals
Dr. Alberto Preda

E-Mail Website
Guest Editor Assistant
Electrophysiology Unit, De Gasperis Cardio Center, Niguarda Hospital, 20162 Milan, Italy
Interests: interventional cardiology; ventricular tachycardia, atrial fibrillation; left atrial appendage occlusion; cardiac electrophysiology

Special Issue Information

Dear Colleagues,

Cardiac ablation is an electrophysiological procedure that involves using energy to create scar tissue within the heart to treat various cardiac arrhythmias. The current status of cardiac ablation reflects its widespread use as an effective treatment option for individuals with abnormal heart rhythms including both ventricular and supraventricular tachycardia. This minimally invasive procedure has demonstrated positive outcomes in restoring normal heart rhythm and improving patients' quality of life as well as in such cases to improve survival. A number of different technologies are used in cardiac ablation including 3D electroanatomic mapping systems, intracardiac echocardiography, steerable catheters, and cerebral protection devices. Moreover, different types of energy are employed, such as radiofrequency, cryoablation, pulsed fields, and laser. Future perspectives in cardiac ablation focus on refining existing techniques, exploring novel technologies, and improving patient outcomes. Advances in catheter design, navigation systems, and mapping technologies aim to enhance the precision and efficacy of the procedure. Additionally, ongoing research investigates alternative energy sources and approaches to further optimize the safety and success rates of cardiac ablation. As the field continues to evolve, personalized and tailored approaches to cardiac ablation may become more prominent, considering individual patient characteristics and specific arrhythmia profiles.

Dr. Fabrizio Guarracini
Guest Editors

Dr. Alberto Preda
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • catheter ablation
  • tachycardia
  • 3D electroanatomic mapping systems
  • intracardiac echocardiography
  • steerable catheters
  • cerebral protection devices

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Other

11 pages, 1094 KiB  
Article
Impact of Ablation Energy Sources on Perceived Quality of Life and Symptom in Atrial Fibrillation Patients: A Comparative Study
by Andrea Matteucci, Maurizio Russo, Marco Galeazzi, Claudio Pandozi, Michela Bonanni, Marco Valerio Mariani, Nicola Pierucci, Vincenzo Mirco La Fazia, Stefania Angela Di Fusco, Federico Nardi and Furio Colivicchi
J. Clin. Med. 2025, 14(8), 2741; https://doi.org/10.3390/jcm14082741 - 16 Apr 2025
Viewed by 226
Abstract
Background: Catheter ablation is a first-line treatment for rhythm control strategies in patients with atrial fibrillation (AF), with different energy sources available, including pulsed-field ablation (PFA), high-power short-duration radiofrequency (HPSD RF), conventional radiofrequency (RF), and cryoballoon ablation. Limited evidence exists on how [...] Read more.
Background: Catheter ablation is a first-line treatment for rhythm control strategies in patients with atrial fibrillation (AF), with different energy sources available, including pulsed-field ablation (PFA), high-power short-duration radiofrequency (HPSD RF), conventional radiofrequency (RF), and cryoballoon ablation. Limited evidence exists on how different ablation techniques affect patient-reported outcomes, such as patients’ quality of life (QoL) and perceived symptoms. This study aims to assess the impact of ablation energy sources on reported QoL and symptom perception after AF ablation. Methods: The study included 148 patients who underwent catheter ablation in different centers. Patients were divided into four groups according to the energy source used. Follow-up was conducted during the 6 months post-procedure. Patients were asked to complete a 20-item questionnaire evaluating quality of life, activity resumption, recovery process, perceived symptoms, and satisfaction. Comparative analyses were performed across energy groups, anesthesia types, and anesthetic drugs. Results: PFA patients reported the highest improvement in QoL scores compared to RF, HPSD RF, and cryoablation (p < 0.001). Activity resumption and symptom relief were significantly better in the PFA group compared to others (p < 0.001). Anesthesia type and anesthetic drug influenced QoL outcomes, with patients under general anesthesia showing higher QoL scores compared to deep sedation (p < 0.001). The energy source and anesthetic drug resulted in independent predictors of QoL improvement. Conclusions: Ablation energy source could impact patients’ perceived QoL and symptom relief after AF ablation. PFA demonstrated superior performance scores in QoL and symptom perception compared to other techniques. Anesthetic drugs also play a role in patient-reported outcomes and activity resumption. Full article
(This article belongs to the Special Issue Cardiac Ablation: Current Status and Future Perspectives)
►▼ Show Figures

Figure 1

12 pages, 2523 KiB  
Article
Radiofrequency Lesion in the Atrial Wall: How Variable Is It? 9.4 Tesla MRI Analysis of Radiofrequency Lesion Volume in a Swine Model
by Laura Sofia Cardelli, Thomas Laumont, July Beghian, Yosra Achahli, Maida Cardoso, Marylène Bacle, Jean-Luc Pasquié and Mathieu Granier
J. Clin. Med. 2024, 13(17), 5153; https://doi.org/10.3390/jcm13175153 - 30 Aug 2024
Viewed by 1169
Abstract
Background/Objectives: Most data on radiofrequency (RF) effects come from ex vivo or in vitro studies that quantify lesions using width and/or depth, while electrophysiologists use manufacturers’ indirect indices. The objective of this study was to evaluate RF lesion volume by high-resolution MRI [...] Read more.
Background/Objectives: Most data on radiofrequency (RF) effects come from ex vivo or in vitro studies that quantify lesions using width and/or depth, while electrophysiologists use manufacturers’ indirect indices. The objective of this study was to evaluate RF lesion volume by high-resolution MRI of excised lesions in an in vivo porcine model, comparing a low-energy long-duration (LE) (20 W, 50 s) RF application strategy with a high-energy short-duration (HE) (50 W, 20 s) one. Methods: Eighteen piglets were divided into LE (n = 9) and HE groups (n = 9). RF applications were performed at four locations in both atria. Animals were sacrificed after 5–7 days, and RF lesion specimens were excised, fixed, and analyzed by 9.4 Tesla MRI. RF lesion volume, variability (variance), depth, and any extracardiac lesions were compared between the groups. Results: Seventy RF applications were performed (36 LE, 34 HE). MRI analyzed 26 LE and 28 HE samples. The HE group showed 35% higher volume than the LE group (100.2 mm3 (±81.2) in LE vs. 178.3 mm3 (±163.7) in HE, p = 0.033). RF volume variance was 6.6 mm3 in LE and 40.3 mm3 in HE. The HE group had more complications (seven vs. zero, p = 0.02) and extracardiac lesions (18 vs. 14, p = 0.613). Conclusions: There was large and unpredictable variability in RF injury on the atrial wall, even under controlled conditions, which could explain arrhythmia recurrences. The greatest lesion variability was found during HE applications. The dose/effect relationship of RF needs careful study for treating cardiac arrhythmias. Full article
(This article belongs to the Special Issue Cardiac Ablation: Current Status and Future Perspectives)
►▼ Show Figures

Figure 1

Other

Jump to: Research

14 pages, 2126 KiB  
Systematic Review
Low-Voltage Area Ablation in Addition to Pulmonary Vein Isolation in Patients with Atrial Fibrillation: A Systematic Review and Meta-Analysis
by Stefano Valcher, Alessandro Villaschi, Giulio Falasconi, Mauro Chiarito, Filippo Giunti, Laura Novelli, Lucio Addeo, Antonio Taormina, Cristina Panico, Pietro Francia, Andrea Saglietto, Guido Del Monaco, Alessia Chiara Latini, Sebastiano Carli, Stefano Frittella, Alessandro Giaj Levra, Giulia Antonelli, Alberto Preda, Fabrizio Guarracini, Patrizio Mazzone, Antonio Berruezo, Massimo Tritto, Gianluigi Condorelli and Diego Penelaadd Show full author list remove Hide full author list
J. Clin. Med. 2024, 13(15), 4541; https://doi.org/10.3390/jcm13154541 - 3 Aug 2024
Cited by 1 | Viewed by 1463
Abstract
Background: Low-voltage area (LVA) ablation, in addition to pulmonary vein isolation (PVI), has been proposed as a new strategy in patients with atrial fibrillation (AF), but clinical trials have shown conflicting results. We performed a systematic review and meta-analysis to assess the impact [...] Read more.
Background: Low-voltage area (LVA) ablation, in addition to pulmonary vein isolation (PVI), has been proposed as a new strategy in patients with atrial fibrillation (AF), but clinical trials have shown conflicting results. We performed a systematic review and meta-analysis to assess the impact of LVA ablation in patient undergoing AF ablation (PROSPERO-registered CRD42024537696). Methods: Randomized clinical trials investigating the role of LVA ablation in addition to PVI in patients with AF were searched on PubMed, Embase, and the Cochrane Library from inception to 22 April 2024. Primary outcome was atrial arrhythmia recurrence after the first AF ablation procedure. Secondary endpoints included procedure time, fluoroscopy time, and procedure-related complication rate. Sensitivity analysis including only patients with LVA demonstration at mapping and multiple subgroups analyses were also performed. Results: 1547 patients from 7 studies were included. LVA ablation in addition to PVI reduced atrial arrhythmia recurrence (odds ratio [OR] 0.65, 95% confidence interval [CI] 0.52–0.81, p < 0.001) with a number needed to treat to prevent recurrence of 10. No difference in procedure time (mean difference [MD] −5.32 min, 95% CI −19.01–8.46 min, p = 0.45), fluoroscopy time (MD −1.10 min, 95% CI −2.48–0.28 min, p = 0.12) and complication rate (OR 0.81, 95% CI 0.40–1.61, p = 0.54) was observed. Consistent results were demonstrated when considering only patients with LVA during mapping and in prespecified subgroups for AF type (paroxysmal vs. persistent), multicentric vs. monocentric trial, and ablation strategy in control group. Conclusions: In patients with AF, ablation of LVAs in addition to PVI reduces atrial arrhythmia recurrence without a significant increase in procedure time, fluoroscopy time, or complication rate. Full article
(This article belongs to the Special Issue Cardiac Ablation: Current Status and Future Perspectives)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop