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Special Issue "Immune Microenvironment in Solid and Hematological Malignancies"
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Hematology".
Deadline for manuscript submissions: 25 May 2023 | Viewed by 6243
Special Issue Editor
Interests: internal medicine; oncology; hematological malignancies; multiple myeloma; emergency
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
It is my pleasure to invite you to contribute to the upcoming Special Issue of the Journal of Clinical Medicine devoted entitled “Immune Microenvironment in Solid and Hematological Malignancies”. The aim of this issue is to provide an overview of current knowledge on the crucial mechanisms promoting tumor niche interactions and mediating immunosuppression during cancer development and progression.
Despite significant improvements in therapy during the last decade, most cancer patients develop refractory disease over time. Treatment of refractory malignancy is a major challenge, likely due to the still poorly characterized inter- and intratumor heterogeneity and the complex interplay of neoplastic cells with the tumor microenvironment. In particular, there is an urgent need to unravel how these features of the cancer neighborhood are linked to molecular mechanisms of drug resistance and aggressive phenotype. The aim of this issue is to review current knowledge on the crucial mechanisms promoting malignant evolution and mediating immunosuppression during cancer development and progression. As is now well known, tumors grow and evolve through a constant crosstalk with the surrounding milieu, and emerging evidence indicates that several gatekeepers and immune-tolerogenic environments frequently occur simultaneously in response to this crosstalk. Accordingly, strategies combining anti-tumor therapy and immunotherapy seem to hold the promise to tip the balance of the cancer niche and improve patient outcomes.
All manuscripts will be peer-reviewed according to standard journal procedures and policies.
I hope that you will be able to accept this invitation and contribute to the success of this Special Issue. I look forward to collaborating with you.
Dr. Antonio G. Solimando
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- immune cells
- immune checkpoints
- tumor angiogenesis