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Early Diagnosis and Early Intervention for Children with Cerebral Palsy
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Early Diagnosis and Early Intervention for Children with Cerebral Palsy

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: closed (1 October 2021) | Viewed by 6269

Special Issue Editors

Dr. Anna Basu

E-Mail Website
Guest Editor
Population Health Sciences Institute, Newcastle University and Paediatric Neurology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK
Interests: early diagnosis and early intervention; perinatal stroke; cerebral palsy; hemiplegia; parent-delivered therapy interventions
Dr. Michael G. Ross

E-Mail Website
Guest Editor
Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Interests: fetal physiology developmental programming hypoxia; acidosis cerebral palsy fetal monitoring

Special Issue Information

Dear Colleagues,

Cerebral palsy (CP) is defined as a group of permanent disorders of the development of movement and posture that cause activity limitations and can be attributed to non-progressive disturbances occurring in the developing fetal or infant brain. The diagnosis is made clinically, and the condition affects around 2/1000 live births. Early intervention has the theoretical potential to provide a greater degree of protection against adverse outcomes due to greater early neuroplasticity. However, several challenges remain. Firstly, early intervention requires accurate early diagnosis, and progress is being made in improving early detection in and the referral of affected infants. Secondly, the evidence base for effective early intervention remains limited. Thirdly, we need to determine how best to support families with a child with CP. This Special Issue aims to collate clinical studies that focus on early detection, evidence-based early intervention, and evidence for the effectiveness of methods of parental support, focussing on the first 1000 days.

Dr. Anna Basu
Dr. Michael G. Ross
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cerebral palsy
  • early diagnosis
  • early intervention
  • therapy
  • first 1000 days
  • parental support

Published Papers (2 papers)

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Research

11 pages, 524 KiB  
Article
Forensic Analysis of Umbilical and Newborn Blood Gas Values for Infants at Risk of Cerebral Palsy
by Michael G. Ross
J. Clin. Med. 2021, 10(8), 1676; https://doi.org/10.3390/jcm10081676 - 14 Apr 2021
Cited by 7 | Viewed by 2295
Abstract
Cerebral palsy litigation cases account for the highest claims involving obstetricians/gynecologists, a specialty that ranks among the highest liability medical professions. Although epidemiologic studies indicate that only a small proportion of cerebral palsy (10–20%) is due to birth asphyxia, negligent obstetrical care is [...] Read more.
Cerebral palsy litigation cases account for the highest claims involving obstetricians/gynecologists, a specialty that ranks among the highest liability medical professions. Although epidemiologic studies indicate that only a small proportion of cerebral palsy (10–20%) is due to birth asphyxia, negligent obstetrical care is often alleged to be the etiologic factor, resulting in contentious medical-legal conflicts. Defense and plaintiff expert opinions regarding the etiology and timing of injury are often polarized, as there is a lack of established methodology for analysis. The objective results provided by umbilical cord and newborn acid/base and blood gas values and the established association with the incidence of cerebral palsy provide a basis for the forensic assessment of both the mechanism and timing of fetal neurologic injury. Using established physiologic and biochemical principles, a series of case examples demonstrates how an unbiased expert assessment can aid in both conflict resolution and opportunities for clinical education. Full article
(This article belongs to the Special Issue Early Diagnosis and Early Intervention for Children with Cerebral Palsy)
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14 pages, 837 KiB  
Article
“It Should Have Been Given Sooner, and We Should Not Have to Fight for It”: A Mixed-Methods Study of the Experience of Diagnosis and Early Management of Cerebral Palsy
by Sîan A Williams, Woroud Alzaher, Anna Mackey, Amy Hogan, Malcolm Battin, Alexandra Sorhage and N Susan Stott
J. Clin. Med. 2021, 10(7), 1398; https://doi.org/10.3390/jcm10071398 - 31 Mar 2021
Cited by 12 | Viewed by 3315
Abstract
Listening to the family experience is integral to identifying areas of strength and for improvement in health service delivery around diagnosis and early management of cerebral palsy (CP). Families of children with a diagnosis of CP were invited to complete a purpose-developed electronic [...] Read more.
Listening to the family experience is integral to identifying areas of strength and for improvement in health service delivery around diagnosis and early management of cerebral palsy (CP). Families of children with a diagnosis of CP were invited to complete a purpose-developed electronic survey that included items around the timing of diagnosis, their experiences and satisfaction. It also allowed families to expand on their experiences through free text. Of the 57 families responding, 49% of children functioned at Gross Motor Function Classification System (GMFCS) levels I or II, 8% at GMFCS level III and 23% at GMFCS levels IV or V. 51% of participants were satisfied or very satisfied with the diagnosis experience, 18% were neutral about the experience and 31% were dissatisfied or very dissatisfied. Though the findings of this study may be subject to selection bias, perceived delays in the receipt of diagnosis of CP appeared common with 60% of participants indicating concerns about their child by <6 months of age but only 21% provided with a diagnosis of CP <6 months of age. Approximately 18% of families experienced a delay of more than 12 months. Thirty-four (61%) participants noted a delay between referrals to a service and receipt of service management/therapy. Common themes impacting on families’ experience in the diagnosis and health service delivery journey related to provision of information, and the style of communication, with both direct and ongoing communication styles common for greater family satisfaction. Overall, families desired the diagnosis experience to be informative and timely, with early follow up support and assistance with health sector navigation. Full article
(This article belongs to the Special Issue Early Diagnosis and Early Intervention for Children with Cerebral Palsy)
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