Advances in Heart Transplantation from Neonatal to Adult Age

Dear Colleagues,

There have been many recent advances in neonatal, pediatric, and adult heart transplantation that are contributing to improved outcomes across all age groups. Some of these, which we would like to highlight in this issue, involve the advanced diagnosis and treatment of antibody mediated rejection, newer induction agents utilized to minimize steroid use or mitigate toxicities of other immunosuppressive agents, and alternative immunosuppressive strategies such as everolimus- or sirolimus-based regimens. In addition, advances in our understanding of donor factors that can affect short- and long-term outcomes following heart transplantation are of recent interest in the field, particularly in the area of predictive outcome models.  We would also like to highlight surgical advances in the field of cardiac transplantation across all age groups, including the use of the Trans Medics Organ Care System (OCS) for donor organ management. Finally, we would like to report on the recent advances in mechanical circulatory support (MCS) as a bridge to heart transplantation, from veno-arterial extra-corporeal membrane oxygenators (VA-ECMO) to ventricular assist devices (VAD) and total artificial hearts (TAH).

Prof. Dr. Massimo Griselli
Dr. Rebecca Ameduri
Dr. Margarita Brida
Prof. Dr. Richard C. Daly
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.