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Insights into Oral and Maxillofacial Surgery
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Insights into Oral and Maxillofacial Surgery

A Special Issue of Journal of Clinical Medicine (ISSN 2077-0383) belonging to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 20 October 2026 | Viewed by 953

Editors

Dr. Gian Battista Bottini

E-Mail Website
Guest Editor
Department of Oral and Maxillofacial Surgery and Center for Reconstructive Surgery, Paracelsus Medical University, 5020 Salzburg, Austria
Interests: oral and maxillofacial surgery; trauma; mandibular condyle fractures; orthognathic surgery; sleep apnea; head and neck cancer; reconstructive surgery; temporomandibular joint; dental implant surgery; dental rehabilitation
Dr. Konstantinos Mitsimponas

E-Mail
Guest Editor
The James Cook University Hospital, Middlesbrough, UK
Interests: oral and maxillofacial surgery; cranio maxillofacial surgery; reconstructive surgery; dental rehabilitation; dental implant surgery

Special Issue Information

Dear Colleagues,

Oral and maxillofacial surgery (OMFS) encompasses a broad spectrum of subspecialties that are continually refined, reflecting the ongoing evolution of techniques and methodologies within the field. This Special Issue aims to provide a comprehensive overview of current clinical advances and emerging trends in OMFS, covering various key areas including trauma management, orthognathic surgery, sleep apnea treatment, head and neck cancer therapies, reconstructive surgery, temporomandibular joint disorders, oral surgery, management of cervicofacial infections, dental implant surgery, and dental rehabilitation.

In each of these subspecialties, innovative practices and research are shaping how we approach patient care, leading to improved outcomes and enhanced quality of life for our patients. We encourage contributors to submit original articles and comprehensive reviews that delve into these crucial sectors, offering novel insights, evidence-based practices, and new perspectives that can advance our understanding and proficiency in OMFS.

Your participation is vital to showcasing the latest advancements and findings in this dynamic field, and we look forward to receiving your submissions that will contribute to the collective knowledge and expertise of our community.

Dr. Gian Battista Bottini
Dr. Konstantinos Mitsimponas
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral and maxillofacial surgery
  • mandibular condyle fractures
  • reconstructive surgery
  • dental rehabilitation
  • dental implant surgery
  • clinical innovation

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

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Research

22 pages, 1040 KB  
Article
Predictors of Severe Course in Odontogenic Cervicofacial Infections: A Prospective Multicenter Cohort Study
by Gian Battista Bottini, Wolfgang Hitzl, Maximilian Götzinger, Benjamin Walch, Florian Huber, Alexander Gaggl, Konstantinos Mitsimponas, Fabrizio Ferretti, Giorgia Cigna, Fabio Roccia and Christoph Steiner
J. Clin. Med. 2026, 15(17), 6930; https://doi.org/10.3390/jcm15176930 - 7 Sep 2026
Abstract
Background: Odontogenic cervicofacial infections are prevalent and can progress to life-threatening conditions, imposing a substantial burden on both patients and healthcare systems. The present study evaluated the association of presentation delay and comorbidities with clinical severity and healthcare resource utilization. Methods: This prospective [...] Read more.
Background: Odontogenic cervicofacial infections are prevalent and can progress to life-threatening conditions, imposing a substantial burden on both patients and healthcare systems. The present study evaluated the association of presentation delay and comorbidities with clinical severity and healthcare resource utilization. Methods: This prospective multicenter cohort study enrolled patients admitted with odontogenic cervicofacial infection at two university hospitals over a one-year period. Demographic and clinical data were systematically collected. Disease severity at presentation was quantified using the Cervicofacial Infection Severity Index (CFISI), a clinically derived composite index incorporating predefined indicators of airway compromise, systemic involvement, and physiological derangement. Results: A total of 61 patients (median age 45 years; range 4–88) were included. The median time to admission was 4 days (IQR 2–5), and the median number of involved anatomical spaces was two (IQR 1–3). The number of involved spaces was significantly associated with a severe clinical course (OR 1.72, 95% CI 1.13–2.63, and p = 0.011). Secondary space involvement correlated with prolonged hospitalization, with a mean length of stay of 11.5 days (95% CI 7.1–15.9) compared to 5.1 days (95% CI 4.6–5.7) in patients without secondary space involvement (p < 0.00001). CFISI was significantly associated with severe clinical course in both univariable (OR 1.16, 95% CI 1.01–1.26, and p = 0.044) and multivariable analyses (OR 1.20, 95% CI 1.01–1.42, and p = 0.042). Increasing age was also independently associated with severe clinical course (OR 1.04 per year, 95% CI 1.00–1.07, and p = 0.028). No predictor demonstrated a significant association with high healthcare resource utilization. Conclusions: Within this cohort, clinical severity was associated with patient age, infection extent, and CFISI. In contrast, delay in presentation and comorbidities did not predict severe outcomes. Secondary space involvement was linked to prolonged hospitalization. No significant predictors of high healthcare resource utilization were identified. Full article
(This article belongs to the Special Issue Insights into Oral and Maxillofacial Surgery)
12 pages, 1390 KB  
Article
Three-Dimensional Changes in Natural Head Position After Bimaxillary Orthognathic Surgery: A Laser-Based Facial Scan Superimposition Study in Skeletal Class II and Class III Patients
by Vincenzo Abbate, Gianluca Renato De Fazio, Francesco Maffia, Eutilia Manzo, Serena Trotta, Marco Friscia, Maria Esposito, Stefania Troise, Giovanni Salzano, Paola Bonavolontà, Fabio Maglitto and Giovanni Dell’Aversana Orabona
J. Clin. Med. 2026, 15(16), 6434; https://doi.org/10.3390/jcm15166434 - 20 Aug 2026
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Abstract
Background/Objectives: Natural head position (NHP) is an important reference for orthodontic and orthognathic assessment. Although postoperative changes in head posture have been reported previously, simultaneous three-dimensional changes across yaw, pitch, and roll in different skeletal classes remain incompletely characterized. This exploratory study quantified [...] Read more.
Background/Objectives: Natural head position (NHP) is an important reference for orthodontic and orthognathic assessment. Although postoperative changes in head posture have been reported previously, simultaneous three-dimensional changes across yaw, pitch, and roll in different skeletal classes remain incompletely characterized. This exploratory study quantified six-month changes in three-dimensional head orientation and compared their direction and magnitude between skeletal Class II and Class III patients. Methods: Fifty-four adults (17 Class II, 37 Class III) undergoing Le Fort I osteotomy and bilateral sagittal split osteotomy were evaluated preoperatively (T0) and 6 months postoperatively (T1). Standardized 3D facial surface acquisitions were obtained using a calibrated structured-light scanner and a fixed external Cartesian laser reference. T0 and T1 datasets were registered using stable upper-facial landmarks (nasion and bilateral exocanthia), and changes in yaw, pitch, and roll were calculated within the common external reference system. Results: Statistically significant T0–T1 changes were observed across all three axes in both skeletal groups (p < 0.01). Class II patients showed mean changes of +2.28° in yaw, −1.30° in pitch, and +2.89° in roll, whereas Class III patients showed +4.61°, +1.96°, and +4.04°, respectively. Between-group differences were significant for yaw, pitch, and roll, with an opposite mean pitch direction and larger mean yaw and roll changes in Class III. Conclusions: At six months, this retrospective cohort demonstrated direction-specific changes in three-dimensional head orientation. Because repeated acquisitions, study-specific observer-reliability and measurement-error analyses, an untreated comparator, an independent validation cohort, and functional or patient-reported outcomes were not available, the findings should be interpreted as exploratory measurements rather than evidence of physiological normalization, neuromuscular adaptation, or clinical benefit. Formal prospective validation is required before the workflow can support predictive or patient management recommendations. Full article
(This article belongs to the Special Issue Insights into Oral and Maxillofacial Surgery)
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18 pages, 26209 KB  
Article
Evaluating Safety and Anatomical Eligibility for Paranasal Implants in the Atrophic Maxilla: A Segmentation-Assisted Proof-of-Concept Study
by Andra Patricia David, Silviu Brad, Laura-Cristina Rusu, Ovidiu Tiberiu David, Andra Ardelean, Robert-Angelo Tuce and Marius Traian Leretter
J. Clin. Med. 2026, 15(12), 4750; https://doi.org/10.3390/jcm15124750 - 18 Jun 2026
Viewed by 307
Abstract
Background/Objectives: Implant placement in transnasal and paranasal regions of the severely atrophic maxilla is challenged by complex anatomy and proximity to critical structures, particularly the nasolacrimal duct (NLD). While cortical anchorage is considered important for implant stability, structured methods for evaluating anatomical [...] Read more.
Background/Objectives: Implant placement in transnasal and paranasal regions of the severely atrophic maxilla is challenged by complex anatomy and proximity to critical structures, particularly the nasolacrimal duct (NLD). While cortical anchorage is considered important for implant stability, structured methods for evaluating anatomical eligibility and anatomical risk during planning remain limited. This proof-of-concept study aimed to describe a segmentation-assisted workflow for anatomical assessment of potential paranasal implant trajectories. Methods: A single-case proof-of-concept workflow was developed using CBCT imaging and multi-component anatomical bone segmentation (MCABS). Segmented anatomical structures were used to selectively visualize cortical pathways within the anterior maxilla. Implant planning was performed using axial, non-tilted trajectories. Particular attention was directed toward visualization of the spatial relationship between the planned implant pathway and the nasolacrimal duct. Workflow feasibility was further explored through study-model fabrication, guided implant insertion, and axis-based verification. Results: The proposed workflow enabled selective visualization of cortical structures and facilitated identification of anatomically favorable implant trajectories within the paranasal region. The relationship between the planned implant pathway and the nasolacrimal duct could be directly assessed using the segmented anatomical model. Guided insertion in the study model demonstrated concordance between planned and executed implant axes, supporting the technical feasibility of the workflow. Conclusions: Within the limitations of a single-case proof-of-concept study, the proposed segmentation-assisted workflow may contribute to preoperative anatomical assessment of potential paranasal implant trajectories and their relationship to adjacent anatomical structures. The workflow should be regarded as a methodological demonstration rather than a validated clinical protocol. Further anatomical, reproducibility, biomechanical, and clinical studies are required before broader clinical adoption can be considered. Full article
(This article belongs to the Special Issue Insights into Oral and Maxillofacial Surgery)
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