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Minimally Invasive and Robotic Surgery for Endometriosis and Gynecologic Malignancies
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Minimally Invasive and Robotic Surgery for Endometriosis and Gynecologic Malignancies

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "General Surgery".

Deadline for manuscript submissions: closed (25 June 2024) | Viewed by 3995

Special Issue Editors

Prof. Dr. Camran R. Nezhat

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Guest Editor
Camran Nezhat Institute, Woodside, CA, USA
Interests: endometriosis; infertility; fibroids; adenomyosis; MIS; reproductive surgery; robotic surgery
Prof. Dr. Farr R Nezhat

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Guest Editor
Weill Cornell Medical College, New York, NY, USA
Interests: gynecologic malignancy; MIS; endometriosis; infertility
Dr. Ceana Nezhat

E-Mail Website
Guest Editor
Nezhat Medical Center, Atlanta, GA, USA
Interests: minimally invasive surgeon; endometriosis; laparoscopy; robotic techniques

Special Issue Information

Dear Colleagues,

Minimally invasive surgery with and without robotic assistance has revolutionized modern day surgery. This revolution started with gynecologic surgery and now has expanded to almost all the disciplines of surgery. This section of the journal addresses minimally invasive and robotic surgical management of the most common benign and malignant disorders that affect millions of women around the world. For example, endometriosis, which is a whole- body disease, will be addressed in this Special Issue. Endometriosis could cause pain, infertility, and organ dysfunction. Authors will write about how endometriosis causes pain and infertility, and its management and outcomes. Additionally, extragenital endometriosis involving the bowel, bladder, ureter, diaphragm, thorax, etc. will be addressed with outcomes. Minimally invasive gynecology with robotic assistance for the management of GYN malignancy will be addressed with outcomes.

Prof. Dr. Camran R. Nezhat
Prof. Dr. Farr R Nezhat
Dr. Ceana Nezhat
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • endometriosis
  • minimally invasive and robotic surgery
  • video-assisted endoscopic surgery
  • laparoscopic surgery
  • gastrointestinal endometriosis
  • genitourinary endometriosis
  • respiratory tract endometriosis
  • extragenital endometriosis
  • video-laparoscopic surgery
  • gynecologic malignancy

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Published Papers (2 papers)

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Research

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16 pages, 2096 KiB  
Article
Superficial Peritoneal Endometriosis Vaporization Using a CO2 Laser: A Long-Term Single-Center Experience
by Stefano Di Michele, Silvia Bramante, Stefano Angioni, Michela Bernassola, Tommaso De Vita, Daniela Anna Iaccarino, Luca Giannoni and Maurizio Rosati
J. Clin. Med. 2024, 13(6), 1722; https://doi.org/10.3390/jcm13061722 - 17 Mar 2024
Cited by 4 | Viewed by 2063
Abstract
Background: The validation of laser usage during laparoscopic procedures, notably by Camran Nezhat in the late 1980s, has been significant. Lasers offer precision and depth control in tissue vaporization without bleeding. Surgical intervention remains central in managing endometriosis-associated pain and infertility, especially [...] Read more.
Background: The validation of laser usage during laparoscopic procedures, notably by Camran Nezhat in the late 1980s, has been significant. Lasers offer precision and depth control in tissue vaporization without bleeding. Surgical intervention remains central in managing endometriosis-associated pain and infertility, especially for patients unresponsive to hormonal therapy. Methods: This retrospective cohort study included 200 patients with superficial peritoneal endometriosis (SPE) who underwent laparoscopic laser vaporization. Surgery was performed using a CO2 laser, and histological confirmation of endometriosis was obtained for all cases. Pain scores and SF-36 questionnaire domains were assessed preoperatively and postoperatively. Fertility outcomes were evaluated among patients desiring pregnancy. Results: Significant improvements in pain score and SF-36 questionnaire domains were observed postoperatively (p-value < 0.01), indicating enhanced quality of life. Among infertile patients with an active desire for pregnancy, surgical treatment showed an overall pregnancy rate after surgery of 93.7% (p-value < 0.01), including 75.7% natural pregnancies and 24.3% IVF. Laser vaporization enabled precise lesion removal with minimal tissue damage, short operative time, and minimal blood loss. Conclusions: Laparoscopic laser vaporization is an effective treatment for SPE, offering pain relief, improved quality of life, and favorable fertility outcomes. Further research is needed to validate these results in terms of pain control and fertility. Full article
(This article belongs to the Special Issue Minimally Invasive and Robotic Surgery for Endometriosis and Gynecologic Malignancies)
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Review

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16 pages, 1111 KiB  
Review
Thoracic Endometriosis Syndrome: A Comprehensive Review and Multidisciplinary Approach to Management
by Camran Nezhat, Nikki Amirlatifi, Zahra Najmi and Angie Tsuei
J. Clin. Med. 2024, 13(24), 7602; https://doi.org/10.3390/jcm13247602 - 13 Dec 2024
Cited by 2 | Viewed by 1373
Abstract
Background: Endometriosis is a systemic, inflammatory, estrogen-dependent condition characterized by endometrial stroma and gland-like lesions outside of the uterus. It causes a range of symptoms, notably chronic pelvic pain, infertility and organ dysfunction. Thoracic endometriosis syndrome (TES) has been described as endometriosis that [...] Read more.
Background: Endometriosis is a systemic, inflammatory, estrogen-dependent condition characterized by endometrial stroma and gland-like lesions outside of the uterus. It causes a range of symptoms, notably chronic pelvic pain, infertility and organ dysfunction. Thoracic endometriosis syndrome (TES) has been described as endometriosis that is found in the lung parenchyma, pleura and diaphragm. It may be asymptomatic or present with symptoms of catamenial pneumothorax, hemothorax, hemoptysis, isolated chest pain, shoulder pain or findings of lung nodules. Aim: The aim of this review is to provide a comprehensive overview of thoracic endometriosis syndrome (TES), including its clinical presentation, diagnostic challenges, and current management strategies. This review aims to highlight the importance of a multidisciplinary approach in the treatment of TES, emphasizing conservative management and the role of minimally invasive surgical techniques for refractory cases. Conclusions: Thoracic endometriosis syndrome appears to be a marker of severe endometriosis. As much as possible, the patient with TES is managed conservatively, with surgery reserved for refractory cases. When surgery is recommended, the procedure is conducted through a multidisciplinary minimally invasive approach, with video-assisted thoracoscopic surgery (VATS) and video-assisted laparoscopy. Meticulous intraoperative survey, the removal of endometriosis implants with and without robotic assistance and post-operative hormonal therapy may be recommended to prevent recurrence. Full article
(This article belongs to the Special Issue Minimally Invasive and Robotic Surgery for Endometriosis and Gynecologic Malignancies)
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