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Current Advances and Challenges in Urological Surgery Using Laser Technologies

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: closed (31 January 2025) | Viewed by 2740

Special Issue Editors


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Guest Editor
Department of Urology AP-HP, Tenon Hospital, Sorbonne University, F-75020 Paris, France
Interests: endourology; minimally invasive surgery; surgical and medical management of stone disease; conservative treatment of UTUC; lower and upper urinary tract diseases

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Guest Editor
Department of Urology AP-HP, Tenon Hospital, Sorbonne University, F-75020 Paris, France
Interests: endourology; minimally invasive surgery; surgical and medical management of stone disease; conservative treatment of UTUC; lower and upper urinary tract diseases
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Special Issue Information

Dear Colleagues,

The field of urology is undergoing rapid advancements with the emergence of novel technologies for the management of lithiasis and the evolution of precision medicine for the treatment of different types of tumors.

Consecutively, urologists are confronting continuous new scientific evidence flow and novel challenges in managing these pathologies. As one of the main scientific fields in urology, laser utilization has been spreading to treat kidney stones and tumors. To appreciate the current evidence on this topic, we propose a Special Issue that focuses on the current advances and challenges in urological surgery using laser technologies. The aim of this Special Issue is to provide readers with the latest updates on these topics.

The subjects of interest for this Special Issue encompass laser applications for urinary stones, upper tract urothelial carcinoma and any tumoral or benign tissue resection/enucleation. The Special Issue is expected to provide valuable insights into preclinical and clinical evidence on these topics which will be of significant interest to urologists, nephrologists and other healthcare professionals involved in the care of patients with urinary tract disorders.

Dr. Frédéric Panthier
Prof. Dr. Olivier Traxer
Guest Editors

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Keywords

  • laser
  • urinary stones
  • upper tract urothelial carcinoma
  • benign prostatic hyperplasia
  • artificial intelligence

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Published Papers (2 papers)

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Research

9 pages, 252 KiB  
Article
Early Hemorrhagic Complications after Holmium Laser Enucleation of the Prostate in Patients Undergoing Antithrombotic Therapy: A Retrospective Analysis from a High-Volume Centre
by Serena Pastore, Marco Carilli, Stefano Di Nicola, Adriano Campagna, Ulderico Parente, Federico Pierella, Giulia D’Ippolito, Enrico Finazzi Agrò and Alessio Zuccalà
J. Clin. Med. 2024, 13(19), 6006; https://doi.org/10.3390/jcm13196006 - 9 Oct 2024
Viewed by 1154
Abstract
Objectives: This study intends to evaluate early hemorrhagic complications after holmium laser enucleation of the prostate (HoLEP) in patients undergoing antithrombotic therapy. Methods: The data of patients undergoing HoLEP between January 2020 and February 2023 were retrospectively analysed. Patients were clustered into three [...] Read more.
Objectives: This study intends to evaluate early hemorrhagic complications after holmium laser enucleation of the prostate (HoLEP) in patients undergoing antithrombotic therapy. Methods: The data of patients undergoing HoLEP between January 2020 and February 2023 were retrospectively analysed. Patients were clustered into three groups: (1) no antithrombotic therapy; (2) antiplatelet (AP) therapy; and (3) anticoagulant (AC) therapy. Pre-, intra-, and post-operative variables were compared. A logistic regression model was built to identify predictors of post-operative hemorrhagic complications. Results: A total of 338 patients underwent HoLEP, including 212 who received no antithrombotic therapy (62.7%), 76 who received AP (22.5%), and 50 who received AC (14.8%). Intra-operative outcomes did not show any significant difference. A significant difference was observed in terms of catheterisation time (p = 0.001) and length of hospital stay (p < 0.001), favouring patients who did not receive antithrombotic therapy. Early post-operative hemorrhagic complications (<30 days) included re-admissions for macrohematuria (3.5%), transfusions (2.4%), and endoscopic re-interventions for bleeding (1.2%). A comparison between the groups showed significant differences for both re-admission (p < 0.001) and transfusion rates (p = 0.01), favouring patients who did not receive antithrombotic therapy. The re-intervention rate did not show any significant difference between the groups (p = 0.1). In multivariate analysis, AC therapy was identified as an independent predictor of those complications (OR 4.9, p = 0.005). Conclusions: HoLEP is a safe and effective procedure for patients undergoing antithrombotic therapy. Both AP and AC therapies are associated with longer catheterisation and hospitalisation times. AC therapy is shown to be a predictor of minor post-operative hemorrhagic complications. Full article
12 pages, 992 KiB  
Article
Multimodal Approach Combining Thulium Laser Vaporization, Bipolar Transurethral Resection of the Prostate, and Bipolar Plasma Vaporization versus Bipolar Transurethral Resection of the Prostate: A Matched-Pair Analysis
by Roxana Andra Coman, Radu Tudor Coman, Răzvan-Ionuț Popescu, Daniel Corneliu Leucuta, Răzvan Couți, Ioan Coman and Nadim Al Hajjar
J. Clin. Med. 2024, 13(16), 4863; https://doi.org/10.3390/jcm13164863 - 17 Aug 2024
Cited by 1 | Viewed by 1223
Abstract
Background/Objectives: The aim of our study is to compare the perioperative and functional outcomes of a multimodal approach combining thulium laser vaporization, bipolar TURP, and bipolar plasma vaporization (TLP) with bipolar TURP in a matched-pair analysis. Methods: A nonrandomized, observational, retrospective, and matched-pair [...] Read more.
Background/Objectives: The aim of our study is to compare the perioperative and functional outcomes of a multimodal approach combining thulium laser vaporization, bipolar TURP, and bipolar plasma vaporization (TLP) with bipolar TURP in a matched-pair analysis. Methods: A nonrandomized, observational, retrospective, and matched-pair analysis was performed on two homogeneous groups of 60 patients who underwent TLP versus bipolar TURP at our center between March 2018 and December 2021. The American Society of Anesthesiologists (ASA) score and prostate volume (PV) were the main parameters used to match patients between the two groups. Follow-up was evaluated at 3, 6, 12, and 24 months after surgery. Results: There was a shorter operative time in favor of TLP (42 versus 45 min, p = 0.402). Median hemoglobin drop (−0.3 versus −0.6, p < 0.001) and median sodium drop (−0.3 versus −0.7, p < 0.001) after surgery were statistically significantly lower in TLP compared to bipolar TURP. The International Prostate Symptom Score (IPSS) and Quality of Life (QoL) scores were significantly lower, and the maximum urinary flow rate was higher in the TLP group. The median PSA decrease 2 years after surgery was 73.92% in the TLP group versus 76.17% in the bipolar TURP group (p = 0.578). The complication rate was lower in the TLP group (20% versus 21.67%, p = 1). Conclusions: The results show that both procedures are equally effective and safe in the treatment of symptomatic BPH with some advantages regarding the TLP technique. Full article
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