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New Insights into Diagnostic and Interventional Radiology
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New Insights into Diagnostic and Interventional Radiology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nuclear Medicine & Radiology".

Deadline for manuscript submissions: 15 May 2025 | Viewed by 3509

Special Issue Editors

Prof. Dr. Domenico Laganà

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Guest Editor
Radiology Unit, Dulbecco University Hospital, University Magna Graecia, 88100 Catanzaro, Italy
Interests: interventional radiology; endovascular interventions; peripheral arterial disease; ablative therapies; interventional oncology; aortic disease
Dr. Roberto Minici

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Guest Editor
Radiology Unit, Dulbecco University Hospital, 88100 Catanzaro, Italy
Interests: interventional radiology; endovascular interventions; peripheral arterial disease; ablative therapies; interventional oncology; ischemic stroke

Special Issue Information

Dear Colleagues,

The Special Issue “New Insights into Diagnostic and Interventional Radiology” in the Journal of Clinical Medicine explores cutting-edge advancements in medical imaging and interventional techniques. Featuring innovative research and clinical applications, this issue delves into emerging technologies, novel diagnostic modalities, and breakthrough interventions that promise to reshape the landscape of radiology. From AI-driven diagnostic tools to minimally invasive interventions, the collection of articles provides a comprehensive overview of the latest developments at the intersection of technology and clinical practice, offering valuable insights for radiologists, clinicians, and researchers navigating the dynamic field of medical imaging and its interventional applications from endovascular interventions to interventional oncology.

Prof. Dr. Domenico Laganà
Dr. Roberto Minici
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • radiomics
  • interventional radiology
  • endovascular interventions
  • interventional oncology
  • ablation therapy
  • locore-gional treatments
  • artificial intelligence
  • peripheral arterial disease (PAD)
  • aortic disease
  • vascular access

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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8 pages, 596 KiB  
Article
Variation in Cone Beam Computed Tomography Utilization and Radiation Exposure Associated with Prostatic Artery Embolization on Two Separate Angiography Systems
by Abin Sajan, Daniel W. Griepp and Ari J. Isaacson
J. Clin. Med. 2024, 13(23), 7403; https://doi.org/10.3390/jcm13237403 - 5 Dec 2024
Viewed by 862
Abstract
Background: We aimed to compare cone beam computed tomography (CBCT) utilization and radiation exposure during prostatic artery embolization (PAE) procedures on two different angiography systems. Methods: PAEs performed by a single interventionalist between January 2018 and October 2020 on two multivendor [...] Read more.
Background: We aimed to compare cone beam computed tomography (CBCT) utilization and radiation exposure during prostatic artery embolization (PAE) procedures on two different angiography systems. Methods: PAEs performed by a single interventionalist between January 2018 and October 2020 on two multivendor angiography systems (AS1 and AS2) at a single center were retrospectively evaluated. Imaging techniques included CBCT acquisition when possible, predominantly from the distal aorta in AS1 and from the bilateral internal iliac arteries in AS2 (Discovery IGS 740, GE HealthCare, Chicago, IL). Baseline demographics, CBCT utilization and radiation doses, and total procedure radiation metrics for each group were collected and compared. Results: One hundred and twenty patients were analyzed in this study, with fifty-three patients (n = 25 in AS1, 28 in AS2) included as embolized bilaterally using CBCT. CBCT was acquired in 31% of the cases in AS1 and in 85% of the cases in AS2. Mean prostate volume was similar in both groups (103.0 mL vs. 130.1 mL, p = 0.23). There was no difference in fluoroscopy time, while the number of DSA series and CBCTs per case did differ in AS1 and AS2 (37.3 min vs. 32.1 min, p = 0.13, 19.8 vs. 8.0, p ≤ 0.001, 1.3 vs. 2.1 p ≤ 0.001). The mean total air kerma, total kerma area product and air kerma per CBCT were higher in AS1 compared to AS2 (2020.4 mGy vs. 490.3 mGy, p ≤ 0.001, 259.3 Gy*cm2 vs. 72.7 Gy*cm2, p ≤ 0.001 and 217.8 mGy vs. 45.8 mGy, p ≤ 0.001 respectively). To prevent confounding from a mean difference in body mass index, the data were adjusted using log outcome means, which corroborated the raw data findings. Conclusions: The mean procedural total kerma area product from AS1 was similar to that reported in other PAE studies, but it was substantially lower in AS2. The angiography system used has a significant impact on the ability to leverage CBCT and on overall patient and thus staff radiation exposure. Full article
(This article belongs to the Special Issue New Insights into Diagnostic and Interventional Radiology)
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13 pages, 940 KiB  
Study Protocol
Ionizing Radiation-Induced Oxidative Stress in Computed Tomography—Effect of Vitamin C on Prevention of DNA Damage: PREVIR-C Randomized Controlled Trial Study Protocol
by Camilo G. Sotomayor, Camila González, Miki Soto, Nicolás Moreno-Bertero, Claudina Opazo, Baltasar Ramos, Gonzalo Espinoza, Álvaro Sanhueza, Gonzalo Cárdenas, Sebastián Yévenes, Jorge Díaz-Jara, José de Grazia, Marcia Manterola, Daniel Castro, Abraham A. I. J. Gajardo and Ramón Rodrigo
J. Clin. Med. 2024, 13(13), 3866; https://doi.org/10.3390/jcm13133866 - 30 Jun 2024
Cited by 1 | Viewed by 2166
Abstract
Exposure to ionizing radiation (IR) is inevitable in various X-ray imaging examinations, with computed tomography (CT) being a major contributor to increased human radiation exposure. Ionizing radiation may cause structural damage to macromolecules, particularly DNA, mostly through an indirect pathway in diagnostic imaging. [...] Read more.
Exposure to ionizing radiation (IR) is inevitable in various X-ray imaging examinations, with computed tomography (CT) being a major contributor to increased human radiation exposure. Ionizing radiation may cause structural damage to macromolecules, particularly DNA, mostly through an indirect pathway in diagnostic imaging. The indirect pathway primarily involves the generation of reactive oxygen species (ROS) due to water radiolysis induced by IR, leading to DNA damage, including double-strand breaks (DSB), which are highly cytotoxic. Antioxidants, substances that prevent oxidative damage, are proposed as potential radioprotective agents. This Study Protocol article presents the rationale for selecting vitamin C as a preventive measure against CT-associated IR-induced DNA damage, to be investigated in a randomized placebo-controlled trial, with a full in vivo design, using an oral easy-to-use schedule administration in the outpatient setting, for the single CT examination with the highest total global IR dose burden (contrast-enhanced abdomen and pelvis CT). The study also aims to explore the mediating role of oxidative stress, and it has been written in adherence to the Standard Protocol Items recommendations. Full article
(This article belongs to the Special Issue New Insights into Diagnostic and Interventional Radiology)
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