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Clinical Diagnosis and Treatment for Spinal Disorders
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Clinical Diagnosis and Treatment for Spinal Disorders

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: closed (15 January 2024) | Viewed by 4421

Special Issue Editors

Prof. Dr. Koji Otani

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Guest Editor
Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan
Interests: epidemiology of musculoskeletal disorders; pathomechanism of spinal pain; nerve root; cauda equina; spinal stenosis; degenerative cervical myelopathy; chronic pain syndrome
Special Issues, Collections and Topics in MDPI journals
Dr. Tadatsugu Morimoto

E-Mail Website
Guest Editor
Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, Japan
Interests: antimicrobial implant; hip-spine syndrome; XR(VR, AR, MR); wearable sensor; locomotive syndrome
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recently, the importance of spinal diseases has been widely recognized, either in terms of quality of life or because of their high prevalence. Spinal diseases are based on age-related degeneration of the spine, but it is a well-known fact that spinal degeneration does not immediately mean symptoms.

Therefore, carefully contrasting imaging findings with clinical symptoms is important, and functional diagnosis is also important.

In addition, advances in diagnostic imaging technology using CT-FEM (CT-based finite element method), AI (artificial intelligence), XR (extended reality) technology, and wearable sensors, all of which have been driven by the recent digital transformation, will provide further breakthroughs in the diagnosis and treatment of spinal disorders. Advances in these technologies are expected to transform not only diagnosis and treatment but also traditional surgical education.

In this Special Issue “Clinical Diagnosis and Treatment for Spinal Disorders”, we are seeking the latest knowledge in the diagnosis and treatment of spinal disorders, including education for surgery. We welcome original articles and reviews of current diagnostics and treatments for spinal disorders that may lead to future clinical research.

Prof. Dr. Koji Otani
Dr. Tadatsugu Morimoto
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • spinal stenosis
  • herniated disc
  • ossification of spinal ligament (OPLL,OLF, etc.)
  • spine deformity
  • spine trauma
  • spinal tumor (primary or metastasis)
  • CT-FEM (CT-based finite element method)
  • AI (artificial intelligence)
  • XR (extended reality)
  • wearable sensor

Published Papers (2 papers)

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Research

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13 pages, 2672 KiB  
Article
Detection of Imperceptible Intervertebral Disc Fissures in Conventional MRI—An AI Strategy for Improved Diagnostics
by Christian Waldenberg, Stefanie Eriksson, Helena Brisby, Hanna Hebelka and Kerstin Magdalena Lagerstrand
J. Clin. Med. 2023, 12(1), 11; https://doi.org/10.3390/jcm12010011 - 20 Dec 2022
Cited by 8 | Viewed by 1633
Abstract
Annular fissures in the intervertebral discs are believed to be closely related to back pain. However, no sensitive non-invasive method exists to detect annular fissures. This study aimed to propose and test a method capable of detecting the presence and position of annular [...] Read more.
Annular fissures in the intervertebral discs are believed to be closely related to back pain. However, no sensitive non-invasive method exists to detect annular fissures. This study aimed to propose and test a method capable of detecting the presence and position of annular fissures in conventional magnetic resonance (MR) images non-invasively. The method utilizes textural features calculated from conventional MR images combined with attention mapping and artificial intelligence (AI)-based classification models. As ground truth, reference standard computed tomography (CT) discography was used. One hundred twenty-three intervertebral discs in 43 patients were examined with MR imaging followed by discography and CT. The fissure classification model determined the presence of fissures with 100% sensitivity and 97% specificity. Moreover, the true position of the fissures was correctly determined in 90 (87%) of the analyzed discs. Additionally, the proposed method was significantly more accurate at identifying fissures than the conventional radiological high-intensity zone marker. In conclusion, the findings suggest that the proposed method is a promising diagnostic tool to detect annular fissures of importance for back pain and might aid in clinical practice and allow for new non-invasive research related to the presence and position of individual fissures. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment for Spinal Disorders)
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Review

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12 pages, 1531 KiB  
Review
Hip–Spine Syndrome: A Focus on the Pelvic Incidence in Hip Disorders
by Tadatsugu Morimoto, Takaomi Kobayashi, Masatsugu Tsukamoto, Hirohito Hirata, Tomohito Yoshihara, Yu Toda and Masaaki Mawatari
J. Clin. Med. 2023, 12(5), 2034; https://doi.org/10.3390/jcm12052034 - 3 Mar 2023
Cited by 2 | Viewed by 2005
Abstract
Since Offierski and MacNab reported a close association between the hip and spine as hip–spine syndrome in 1983, many studies on spinal alignment in hip disorders have been conducted. Notably, the pelvic incidence angle (PI) is the most important parameter and is determined [...] Read more.
Since Offierski and MacNab reported a close association between the hip and spine as hip–spine syndrome in 1983, many studies on spinal alignment in hip disorders have been conducted. Notably, the pelvic incidence angle (PI) is the most important parameter and is determined by the anatomical variations in the sacroiliac joint and hip. Studies on the association of the PI with hip disorders can help in understanding the pathophysiology of hip–spine syndrome. A PI increase has been observed during the evolution of bipedal locomotion in humans and in the acquisition of gait during child development. Although the PI is a fixed parameter that is stable and unaffected by posture from adulthood onwards, it has become clear that it increases in the standing position in older people. While it may be associated with a greater risk of developing or progressing to spinal disorders, the association between the PI and hip disorders remains controversial because of the multifactorial nature of hip osteoarthritis (HOA) and the wide range of PIs in HOA (18–96°), making the interpretation of results difficult. However, several hip disorders (i.e., femoroacetabular impingement and rapid destructive coxarthrosis) have been shown to be associated with the PI. Further investigation on this topic is, therefore, warranted. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment for Spinal Disorders)
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