Recent Developments in Mitral Valve Repair

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 2616

Special Issue Editor


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Guest Editor
Division of Cardiac Surgery, IRCCS Foundation Hospital San Matteo, Piazzale Golgi, 1, 20123 Pavia, Italy.
Interests: heart transplantation; mechanical supports; mitral valve repair; minimal access surgery; beating heart surgery; patient-prosthesis mismatch following valve surgery

Special Issue Information

Dear Colleagues,

The mitral valve is an important valve in the heart, and its dysfunction may lead to backflow of blood and increased load on the heart. Mitral valve repair is an important cardiac procedure used to treat mitral valve disease. This special issue will cover the following aspects:

  1. Innovation in surgical technology: including visualization-assisted technology, three-dimensional reconstruction technology, robot-assisted surgery, etc.
  2. Progress in interventional therapy: In addition to traditional thoracotomy, interventional therapy has also made important breakthroughs in the field of mitral valve repair. Through catheter technology, doctors can perform mitral valve repair without opening the chest, reducing surgical trauma and recovery time.
  3. Personalized treatment and complication management.

We invite researchers in the field of mitral valve related areas to submit their findings as original articles or reviews to this special issue.

Dr. Pasquale Totaro
Guest Editor

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Keywords

  • mitral valve repair
  • minimally invasive mitral valve surgery
  • robotic surgery
  • mitral regurgitation
  • transcatheter mitral valve replacement

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Published Papers (1 paper)

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Review

22 pages, 708 KiB  
Review
Atrial Functional Mitral Regurgitation: From Diagnosis to Current Interventional Therapies
by Panagiotis Iliakis, Kyriakos Dimitriadis, Nikolaos Pyrpyris, Eirini Beneki, Panagiotis Theofilis, Panagiotis Tsioufis, Vasileios Kamperidis, Konstantinos Aznaouridis, Konstantina Aggeli and Konstantinos Tsioufis
J. Clin. Med. 2024, 13(17), 5035; https://doi.org/10.3390/jcm13175035 - 25 Aug 2024
Cited by 3 | Viewed by 2200
Abstract
Mitral regurgitation (MR) is one of the most common valvular pathologies worldwide, contributing to the morbidity and mortality of several cardiovascular pathologies, including heart failure (HF). Novel transcatheter treatment for MR has given the opportunity for a safe and feasible alternative, to surgery, [...] Read more.
Mitral regurgitation (MR) is one of the most common valvular pathologies worldwide, contributing to the morbidity and mortality of several cardiovascular pathologies, including heart failure (HF). Novel transcatheter treatment for MR has given the opportunity for a safe and feasible alternative, to surgery, in order to repair the valve and improve patient outcomes. However, after the results of early transcatheter edge-to-edge repair (TEER) trials, it has become evident that subcategorizing the mitral regurgitation etiology and the left ventricular function, in patients due to undergo TEER, is of the essence, in order to predict responsiveness to treatment and select the most appropriate patient phenotype. Thus, a novel MR phenotype, atrial functional MR (AFMR), has been recently recognized as a distinct pathophysiological entity, where the etiology of the regurgitation is secondary to annular dilatation, in a diseased left atrium, with preserved left ventricular function. Recent studies have evaluated and compared the outcomes of TEER in AFMR with ventricular functional MR (VFMR), with the results favoring the AFMR. In specific, TEER in this patient substrate has better echocardiographic and long-term outcomes. Thus, our review will provide a comprehensive pathogenesis and mechanistic overview of AFMR, insights into the echocardiographic approach of such patients and pre-procedural planning, discuss the most recent clinical trials and their implications for future treatment directions, as well as highlight future frontiers of research in the setting of TEER and transcatheter mitral valve replacement (TMVR) in AFMR patients. Full article
(This article belongs to the Special Issue Recent Developments in Mitral Valve Repair)
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