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Advances in Diagnosis and Treatment of Thyroid Disorders
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Advances in Diagnosis and Treatment of Thyroid Disorders

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Endocrinology & Metabolism".

Deadline for manuscript submissions: closed (28 February 2025) | Viewed by 647

Special Issue Editors

Dr. Eleonora Lori

E-Mail Website
Guest Editor
Department of Surgery, Sapienza University of Rome, 00161 Rome, Italy
Interests: thyroid cancer; primary hyperparathyroidism; endocrine surgery
Prof. Dr. Salvatore Ulisse

E-Mail Website
Guest Editor
Department of Surgical Sciences, “Sapienza” University of Rome, Viale Regina Elena, 324, 00161-Rome, Italy
Interests: Iodine nutrition; iodine deficiency disorders; thyroid diseases; diagnosis; prognosis and therapy of thyroid cancers; cell cycle regulation; thyroid hormones; male and female reproduction systems
Dr. Salvatore Sorrenti

E-Mail Website
Guest Editor
Department of Surgical Sciences, Sapienza University of Rome, 00161 Rome, Italy
Interests: thyroid cancer; breast cancer; surgical oncology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue on “Advances in Diagnosis and Treatment of Thyroid Disorders” provides a comprehensive overview of the innovations shaping thyroid pathology and treatment. It highlights the role of technological advancements in enhancing diagnostic accuracy, ensuring timely and appropriate care. Innovations in imaging technologies, such as CEUS and Elastosonography, and the integration of artificial intelligence and machine learning are refining the accuracy and speed of diagnosing thyroid conditions.

The Issue emphasizes the impact of new surgical technologies and approaches in the surgical treatment of thyroid diseases. Minimally invasive techniques, but also robotic and endoscopic thyroidectomy, are improving esthetic outcomes, setting new standards for surgical care.

This Special Issue will also aim to deepen the management of thyroid diseases through tailored therapeutic approaches and personalized therapies, leveraging the clinical applications of molecular biology.

Bringing together these advancements, this Issue provides a holistic view of thyroid disorder diagnosis and treatment, underscoring the interdisciplinary nature of modern medical practice. It aims to be a valuable resource for clinicians, researchers, and healthcare professionals dedicated to thyroid pathology.

Dr. Eleonora Lori
Prof. Dr. Salvatore Ulisse
Dr. Salvatore Sorrenti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • thyroid surgery
  • targeted therapy
  • goiter
  • papillary thyroid cancer
  • medullary thyroid cancer
  • artificial intelligence
  • ultrasound imaging
  • minimally invasive approach
  • remote access
  • molecular biomarkers

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Published Papers (1 paper)

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14 pages, 1089 KiB  
Review
Acute Suppurative and Subacute Thyroiditis: From Diagnosis to Management
by Tommaso Toschetti, Cecilia Parenti, Ilaria Ricci, Irene Addati, Sonia Diona, Susanna Esposito and Maria Elisabeth Street
J. Clin. Med. 2025, 14(9), 3233; https://doi.org/10.3390/jcm14093233 - 7 May 2025
Viewed by 295
Abstract
Background: Acute suppurative thyroiditis (AST) and subacute thyroiditis (SAT) are two distinct inflammatory conditions of the thyroid gland with different clinical presentation and treatment and that recognize different causes. AST is a rare but serious bacterial infection, often associated with congenital anomalies [...] Read more.
Background: Acute suppurative thyroiditis (AST) and subacute thyroiditis (SAT) are two distinct inflammatory conditions of the thyroid gland with different clinical presentation and treatment and that recognize different causes. AST is a rare but serious bacterial infection, often associated with congenital anomalies in children, whereas SAT is a self-limiting, post-viral condition that causes temporary thyroid dysfunction. Methods: A comprehensive literature review was conducted using PubMed and UpToDate, including systematic reviews, meta-analyses, case series, and case reports. Studies focusing on epidemiology, pathophysiology, clinical presentation, diagnosis, and treatment were selected, with special attention paid to pediatric cases. Results: AST accounts for fewer than 1% of thyroid diseases and is more common in children, with pyriform sinus fistulas being present in 21% of cases. It presents with fever, painful neck swelling, and complications such as abscess formation and airway obstruction. Early recognition and prompt management with broad-spectrum antibiotics, ultrasound-guided aspiration, or surgical drainage are crucial. In contrast, SAT can occur at any age but is most common in adult women and typically follows a viral infection. It presents with anterior neck pain and transient thyrotoxicosis and is generally managed with non-steroidal anti-inflammatory drugs or corticosteroids in severe cases. Accurate differential diagnosis is essential to prevent unnecessary interventions. Conclusions: Although rare, both AST and SAT require timely diagnosis and tailored treatment strategies to avoid complications. Advances in imaging and the early detection of congenital anomalies have improved AST outcomes, while SAT remains a self-limiting condition that primarily requires symptom management. Further research is needed to better understand risk factors, pathogenesis, and optimal treatment approaches, particularly in pediatric populations and resource-limited settings. Full article
(This article belongs to the Special Issue Advances in Diagnosis and Treatment of Thyroid Disorders)
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