Clinical Perspectives in Amyotrophic Lateral Sclerosis: Diagnosis, Management and Future Opportunities
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".
Deadline for manuscript submissions: 15 February 2026 | Viewed by 15
Special Issue Editor
Interests: amyotrophic lateral sclerosis; sleep; non-invasive ventilation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
I am happy to announce a new Special Issue on ALS that has been launched by JCM and that I have the honor to introduce as guest editor. This Special Issue will encompass 8 contributions and is dedicated to recent advances regarding diagnostic methods, treatment options, and upcoming developments in ALS research and care. ALS is still a devastating condition that almost inevitably leads to muscle wasting, progressive loss of motor functions, respiratory failure, and premature death. However, our understanding of genetic causes and molecular disease mechanisms, but also of the phenotypic spectrum that implies immanently distinct prognostic features, has become much deeper in recent years. Most important, innovative therapeutic strategies have emerged that promise tailored, individualized treatment options for subsets of affected people. Against all odds, some of the latter have shown their potential to stabilize or even improve function in a condition that usually comes with permanent losses and lasting deficits.
Thus, early, accurate, and comprehensive diagnosis will become ever more pivotal, and this issue explores advances in neuroimaging and biomarkers that promise to enhance diagnostic precision. In parallel, the Special Issue is open to reports on evolving strategies in disease management, including pharmacologic treatments, multidisciplinary care models, assistive technologies, and palliative interventions that all aim to improve quality of life and extend survival. By integrating contributions from leading experts across neurology, bioengineering, and translational science, this Special Issue aims to provide a comprehensive overview of the field and a forum that fosters knowledge exchange and stimulates innovation, ultimately paving the way toward deeper understanding and more effective interventions.
Prof. Dr. Matthias Boentert
Guest Editor
Manuscript Submission Information
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Keywords
- amyotrophic lateral sclerosis
- early diagnosis
- neuroimaging
- biomarkers
- treatment
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