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Clinical Diagnosis and Treatment of Gynecologic Oncology
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Clinical Diagnosis and Treatment of Gynecologic Oncology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".

Deadline for manuscript submissions: closed (20 September 2024) | Viewed by 2061

Special Issue Editors

Dr. Federica Perelli

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Guest Editor
Department of Woman and Child Health, Obstetrics and Gynecology, Santa Maria Annunziata Hospital, Florence, Italy
Interests: gynecologic oncology; fertility-sparing program; pediatric gynecology; minimally invasive surgery; endometriosis
Special Issues, Collections and Topics in MDPI journals
Dr. Marco D'Indinosante

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Guest Editor
Department of Woman and Child Health, IRCCS Fondazione Policlinico Agostino Gemelli, 00168 Rome, Italy
Interests: gynecologic oncology; fertility-sparing program; minimally invasive surgery; ovarian cancer; cervical cancer; endometrial cancer

Special Issue Information

Dear Colleagues,

Today, the multidisciplinary management of patients with gynecological cancers represents a continuous challenge. This is mainly due to the two main outcomes for this subset of patients: survival, related to adequate and radical treatment, and quality of life, linked to the chance to be submitted to minimally invasive surgery that aims to preserve the reproductive and hormonal functionality of young patients and reduce postoperative morbidity. The development of treatment pathways aimed at maintaining a good quality of life and fertility for young patients is still investigated and debated today. Even postmenopausal patients can benefit from the use of less invasive surgical techniques and medical therapies, both in terms of a minimally invasive approach, such as the sentinel lymph node technique, and for a reduction in exposure to toxic drugs or radiation based on the prognostic stratification, including elements of molecular biology.

The aim of this Special Issue is to provide a comprehensive overview of the advances in the diagnosis, prognostic stratification, and treatment of gynecologic oncologic patients. Therefore, researchers in the field of gynecologic oncology, surgical oncology, and reproductive medicine are encouraged to submit their findings as original articles or reviews to this Special Issue.

Dr. Federica Perelli
Dr. Marco D'Indinosante
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gynecologic oncology
  • minimally invasive surgery
  • sentinel lymph node
  • fertility-spring surgery
  • molecular biology

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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13 pages, 2093 KiB  
Article
Ovarian Cancer Staging—How CT Scan Descriptions Differ from Surgical Findings
by Adrianna Ćwiertnia, Dominika Borzyszkowska, Anna Golara, Natalia Tuczyńska, Mateusz Kozłowski, Wojciech Poncyljusz, Agnieszka Sompolska-Rzechuła, Katarzyna Kotrych and Aneta Cymbaluk-Płoska
J. Clin. Med. 2024, 13(15), 4560; https://doi.org/10.3390/jcm13154560 - 5 Aug 2024
Viewed by 804
Abstract
Ovarian cancer is one of the most common causes of cancer death in women worldwide. Most often, it is detected in an advanced stage due to its insidious onset and lack of symptoms in stages I and II. That is why imaging diagnostics [...] Read more.
Ovarian cancer is one of the most common causes of cancer death in women worldwide. Most often, it is detected in an advanced stage due to its insidious onset and lack of symptoms in stages I and II. That is why imaging diagnostics is so important. Therefore, we assessed the consistency of the image seen on CT with the actual image assessed during surgery. Objectives: The aim of this study is to compare preoperative evaluation based on CT reports with those obtained during ovarian cancer surgery to determine whether CT is helpful in assessing the possibility of optimal or complete cytoreduction. Methods: This retrospective study included patients diagnosed with ovarian cancer who underwent diagnostic laparoscopy or laparotomy with cytoreduction. We compared ovarian cancer lesions described by radiologists on CT scans to those described during laparoscopy or laparotomy; the Wilcoxon signed-rank test for paired observations was used to compare the variables. Results: We observed that the morphology of the tumor, mesenteric infiltration, and the assessment of the involvement of the abdominal, para-aortic, and iliac lymph nodes may differ in CT examination and during surgery. Conclusions: The site of the tumor exit on a CT scan does not always reflect the original site seen during surgery. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Gynecologic Oncology)
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Review

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24 pages, 3688 KiB  
Review
Tubal Cancer Clinical Management: Two Exceptional Scenarios and a Review of the Literature
by Irene Colombi, Marco D’Indinosante, Lucia Lazzeri, Errico Zupi, Silvia Pisaneschi, Marco Giusti, Alberto Mattei, Elisa Valentina Debonis, Angelo Cassisa, Anna Franca Cavaliere and Federica Perelli
J. Clin. Med. 2024, 13(17), 5075; https://doi.org/10.3390/jcm13175075 - 27 Aug 2024
Viewed by 765
Abstract
This article provides a literature review on tubal carcinoma to offer an updated insight into its preventative strategies, diagnosis, treatment and oncological surveillance. In addition to the search string utilized, the authors’ focus extended to key scientific studies, consensus statements, guidelines and relevant [...] Read more.
This article provides a literature review on tubal carcinoma to offer an updated insight into its preventative strategies, diagnosis, treatment and oncological surveillance. In addition to the search string utilized, the authors’ focus extended to key scientific studies, consensus statements, guidelines and relevant case reports essential for the proper clinical management of the disease, providing a methodologically well-structured literature review combined with practical expertise in the oncological field. This article also includes two special clinical cases that emphasize the importance of understanding the physiopathology and the current state of the art in the anatomopathological advancements in tubal/ovarian/peritoneal carcinoma, often assimilated into a single clinical entity and to which many of the concepts extracted from the literature can apply. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Gynecologic Oncology)
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