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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Next-Gen Tissue Engineering in Disease Modelling, Drug Discovery and Immunotherapeutics submission deadline 20 Oct 2025 | 1 articles | Viewed by 753 | Submission Open
Keywords: tissue engineering; 3D cell culture; biomaterials; disease modelling; immunotherapy; cell-based therapies; organ-on-a-chip
(This special issue belongs to the Section Molecular Biology)
New Molecular Progression of Movement Disorders submission deadline 20 Oct 2025 | 1 articles | Viewed by 747 | Submission Open
Keywords: movement disorders; molecular mechanisms; neurodegenerative diseases; therapeutic targets; biomarkers; neuroinflammation; protein misfolding; mitochondrial dysfunction; environmental factors; genetic factors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Molecular Mechanisms of Genotoxicity
edited by Francesca Marcon and
submission deadline 20 Oct 2025 | Viewed by 745 | Submission Open
Keywords: DNA damage; DNA repair; genotoxicity; carcinogenesis; chronic degenerative diseases; human health; molecular mechanisms
(This special issue belongs to the Section Molecular Toxicology)
Yeast Modeling in Metabolism and Cell Cycle Research submission deadline 20 Oct 2025 | Viewed by 742 | Submission Open
Keywords: yeast modeling; metabolism; cell cycle development; microbial fermentation; bioactive compounds; probiotics; drug targets
(This special issue belongs to the Section Molecular Biology)
Biological Activities and Structure–Activity Relationships of Natural and Non-Natural Compounds
edited by
submission deadline 20 Oct 2025 | 1 articles | Viewed by 729 | Submission Open
Keywords: natural compounds; synthetic compounds; biological activities; structure– activity relationship (SAR); bioavailability; toxicity; computational modeling; drug delivery; nanomedicine
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Regulation of Ion Channels and Transporters
edited by
submission deadline 20 Oct 2025 | 1 articles | Viewed by 690 | Submission Open
Keywords: ion channels; ion transporters; cardiovascular disease; inflammatory disease; cancers; neurogenerative disease; disease microenvironment; drug discovery; drug resistance
(This special issue belongs to the Section Molecular Biology)
Molecular Research on Chronic Kidney Disease
edited by
submission deadline 20 Oct 2025 | Viewed by 690 | Submission Open
Keywords: CKD; CVD; CKD-MBD; oxidative stress; inflammation; fibrosis; biochemical markers
(This special issue belongs to the Section Molecular Biology)
Molecular Advances in Functional Products for Health Prevention and Promotion
edited by
submission deadline 20 Oct 2025 | 1 articles | Viewed by 670 | Submission Open
Keywords: functional foods; food fortification; biofortification; bioactive food ingredients; human nutrition; nutrition and immunity; health prevention; chronic non-communicable diseases; epigenetics
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Complications of Pregnancy: The Importance of Omics-Based Diagnosis and Therapeutic Approaches submission deadline 20 Oct 2025 | 1 articles | Viewed by 666 | Submission Open
Keywords: pregnancy complications; epigenetics; omics; miRNA-based therapies; microbiome analysis; early diagnosis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Regulatory Mechanisms in the Hypoxic Environment
edited by Irene Filippi
submission deadline 20 Oct 2025 | 1 articles | Viewed by 643 | Submission Open
Keywords: hypoxia; hypoxia-inducible factors (HIFs); angiogenesis; metabolic adaptation; autophagy; cell survival; chronic obstructive pulmonary disease (COPD); cancer
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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