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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genetics and Omics in Autoimmune Diseases submission deadline 30 Sep 2025 | Viewed by 28 | Submission Open
Keywords: autoimmune diseases; genetics; genomics; omics; single-nucleotide variants; copy number variants; variation; susceptibility; mRNAs; microRNAs; long non-coding RNAs; masive sequencing
(This special issue belongs to the Section Molecular Genetics and Genomics)
Hydrogels and Nanogels: Revolutionizing Drug Delivery and Disease Detection
edited by Enrico Gallo
submission deadline 30 Sep 2025 | Viewed by 28 | Submission Open
Keywords: hydrogel and nanogel networks; supramolecular systems; hydrogel synthesis and analysis; nanogel preparation and characterization; nanostructured fibers; multiphase gels; biomedicine applications; supramolecular probes for imaging; hydrogels and nanogels as drug release systems; coatings and surface treatments; polymeric systems; peptide-based supramolecular systems
(This special issue belongs to the Section Materials Science)
Molecular Mechanisms of Mitochondrial Neurodegenerative Diseases
edited by and Paola Pontieri
submission deadline 30 Sep 2025 | Viewed by 28 | Submission Open
Keywords: mitochondrial disease; nuclear genome; mitochondrial genome; human MRP genes; MRPL44; NAM9; GEP3; Alzheimer’ s disease; Parkinson’ s disease; yeast and C. elegans model organisms
(This special issue belongs to the Section Molecular Neurobiology)
Design, Synthesis and Application of Cellulose Materials
edited by and
submission deadline 30 Sep 2025 | Viewed by 28 | Submission Open
Keywords: cellulose; polymer materials; biomass
(This special issue belongs to the Section Materials Science)
Biochemical Advancements in Filler Technology and Their Impact on Tissue Engineering
edited by Samuel J. Lin
submission deadline 30 Sep 2025 | Viewed by 28 | Submission Open
Keywords: biochemical filler technology; tissue regeneration; bioactive materials; injectable scaffolds; molecular signaling in tissue engineering; biomaterials for soft tissue repair; filler– cell interactions; regenerative esthetics
(This special issue belongs to the Section Biochemistry)
Molecular Pathogenesis and Therapeutic Innovations in Oral Diseases
edited by Tatsuji Nishihara
submission deadline 30 Sep 2025 | Viewed by 27 | Submission Open
Keywords: molecular-based analysis; diagnosis of oral disease; oral disease treatment; regeneration therapy; drug therapy; periodontitis; implantitis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Surfactant Sciences: Design, Synthesis, and Applications
edited by Zakaria Hafidi
submission deadline 30 Sep 2025 | Viewed by 27 | Submission Open
Keywords: surfactants; synthesis; biodegradation; catalysis; biological activity; nanoparticles; design; green chemistry; self-assembly; surface chemistry
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Lifestyle Interventions in MASLD: A Molecular Perspective
edited by Muhammad Y. Sheikh
submission deadline 30 Sep 2025 | Viewed by 27 | Submission Open
Keywords: NAFLD (nonalcoholic fatty liver disease); MASLD (metabolic syndrome-associated steatotic liver disease); metabolic syndrome; dyslipidemia; diabetes mellitus 2; hypertension; natural bioactive
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Endoplasmic Reticulum Stress and Apoptosis—Second Edition submission deadline 30 Sep 2025 | Viewed by 27 | Submission Open
Keywords: ER stress; apoptosis initiated by ER stress; cellular survival; redox homeostasis of ER; autophagy initiated by ER stress; cell death pathways initiated by ER stress
(This special issue belongs to the Section Biochemistry)
Molecular Research in Natural Products
edited by
submission deadline 30 Sep 2025 | Viewed by 26 | Submission Open
Keywords: synaptic plasticity regulation; bioactive compounds; signal transduction pathways; gene expression regulation; molecular neurobiology
(This special issue belongs to the Section Bioactives and Nutraceuticals)
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