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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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RNA in Human Diseases: Challenges and Opportunities: 2nd Edition
edited by
submission deadline 30 Sep 2025 | Viewed by 34 | Submission Open
Keywords: microRNA; piRNA; lncRNA; circRNA; RNA therapeutics; ceRNET; RNA disease; RNA processing; RNA modification
(This special issue belongs to the Section Molecular Biology)
Alzheimer’s Disease: Molecular Mechanisms and Novel Therapies
edited by Noah R. Johnson and
submission deadline 30 Sep 2025 | Viewed by 33 | Submission Open
Keywords: intrinsically disordered proteins; apolipoproteins; neuroinflammation and neuroimmune; autolysosomal and mitochondrial functions; lipid metabolism; blood-brain barrier; biosensors; nanomedicine; high-throughput screening; therapeutic discovery
(This special issue belongs to the Section Molecular Neurobiology)
Mitochondrial Functions and Dynamics
edited by
submission deadline 30 Sep 2025 | Viewed by 33 | Submission Open
Keywords: bioenergetics; mitochondrial biogenesis; mitochondrial morphology; apoptosis; mitophagy; reactive oxygen species; calcium homeostasis; cardiovascular diseases; neurodegenerative diseases; in vitro; cellular; and animal models; myopathies; mitochondria and immune system
(This special issue belongs to the Section Molecular Biology)
Advances in Surfactant Systems: Thermodynamics, Molecular Interactions, and Applications
edited by
submission deadline 30 Sep 2025 | Viewed by 33 | Submission Open
Keywords: micelles; mixed micelles; thermodynamic functions of micellization; micellar solubilization; enthalpy– entropy compensation; boundary surface; Langmuir isotherm; theoretical models
(This special issue belongs to the Section Biochemistry)
The Role of Extracellular Vesicles in Disease and Therapeutic Applications
edited by Sunyoung Park
submission deadline 30 Sep 2025 | Viewed by 33 | Submission Open
Keywords: extracellular vesicles (EVs); disease biomarkers; EV-based therapeutics; cancer diagnosis; drug delivery; immune modulation; regenerative medicine
(This special issue belongs to the Section Molecular Biology)
Recent Advance in Immunosuppressive Therapy
edited by
submission deadline 30 Sep 2025 | Viewed by 32 | Submission Open
Keywords: immunosuppressive drugs; calcineurin inhibitors; corticosteroids; inhibitors of purine synthesis; mammalian target of rapamycin inhibitors; biological treatment; cell-based therapies; biomarkers; genetic profiling
(This special issue belongs to the Section Molecular Immunology)
Genetic, Functional and Therapeutic Aspects of Procoagulant and Anticoagulant Factors (Third Edition)
edited by and
submission deadline 30 Sep 2025 | Viewed by 31 | Submission Open
Keywords: procoagulant factors; anticoagulant factors; hemostasis; inflammation; genetics; therapeutics; cell signaling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Neuroendocrine Integration of Stress and Reproduction
edited by Maria Bernardete Cordeiro De Sousa
submission deadline 30 Sep 2025 | Viewed by 31 | Submission Open
Keywords: HPA axis; HPG axis; stress and reproduction; neuroendocrine regulation; cortisol and fertility; neuropeptides; epigenetics; reproductive dysfunction
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Insights into Probiotics and Prebiotics in Gut Health and Disease
edited by
submission deadline 30 Sep 2025 | Viewed by 31 | Submission Open
Keywords: probiotics; prebiotics; gut microbiota; intestinal health; dysbiosis; host– microbe interactions; omics; gut– brain axis
(This special issue belongs to the Section Molecular Microbiology)
Advances in the Molecular Biology of Lipids and Mitochondria
edited by
submission deadline 30 Sep 2025 | Viewed by 31 | Submission Open
Keywords: lipids; lipid transport mechanisms; lipid peroxidation; mitochondrial integrity; bioenergetics; mitochondrial phospholipid
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
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