Tumor Microenvironment from a Precision Medicine Perspective

Dear Colleagues,

Tumor biology research has increasingly focused on the tumor microenvironment—a complex network of resident and infiltrating non-malignant host cells, extracellular matrix proteins, and secreted factors within and around a tumor. The tumor microenvironment has a highly dynamic composition and delivers survival, proliferation, and/or immune modulatory signals to malignant cells via cellular interactions, secreted proteins, and metabolites. This intricate interplay also defines distinct niches in different malignancies and individual patients.

This Special Issue will host review, opinion, and research articles that focus on the composition of the tumor microenvironment, especially in relation to therapeutic and diagnostic approaches. We particularly welcome articles exploring strategies to define individual liabilities related to tumor microenvironment and tumor interactions, with personalized therapies as the final outcome. Special attention will be given to articles based on interdisciplinary research, e.g., (pre)clinical models in combination with omics, imaging, and/or bioinformatics analyses.

Dr. Alexander Deutsch
Dr. Julia Feichtinger
Dr. Jelena Krstic
Dr. Katharina Prochazka
Guest Editors

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