Special Issue "Protein Structure Dynamics and Function"
Deadline for manuscript submissions: 31 August 2021.
2. Research Center for the Mathematics on Chromatin Live Dynamics (RcMcD), Hiroshima University, 1-3-1, Kagamiyama, Higashi-Hiroshima 739-8526, Japan
Interests: protein structure; protein structural dynamics; intrinsically disordered protein; protein aggregation; nuclear magnetic resonance spectroscopy
Special Issues and Collections in MDPI journals
Protein structural dynamics is intimately related to protein functions. Structure biology demands high-resolution structures primarily coming from X-ray crystallography. However, the crystal structure does not always give a comprehensive understanding of the functional mechanism. This inability is often ascribed to a lack of insight into the time-dependent spatial rearrangement of the regulatory residues, domains, and subunits in proteins, which emphasizes the importance in exploring how structural dynamics engages in functional regulation in proteins. Progress in the experimental and theoretical approaches has improved our understanding of protein structural dynamics and has updated the protein structure and function relationships by adding the roles of structural dynamics. The technical advances have also expanded the research targets from folded proteins to intrinsically disordered proteins that travel much wider conformational spaces over the folded proteins. Intrinsically disordered proteins with liquid–liquid phase separation properties have become focused, which unveils the other remarkable roles of structural dynamics in regulating the phase transition of the protein solution.
The Special Issue “Protein Structure Dynamics and Function” is a continuation of the successful 2018 and 2019 issue “Protein Structural Dynamics.” This issue also aims to present contemporary research on protein structural dynamics, which may include original articles covering technical development, experimental reports on some particular proteins, and theoretical research, as well as review papers relating to the topic.
Prof. Dr. Shin-ichi Tate
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Protein strutural dynamics
- Enzyme functions
- Intrinsically disordered proteins
- Single molecular FRET (fluorecense resonance energy transfer)
- Molecular dynamics simulation
- Coarse grained molecular dynamics simulation