Positron Emission Tomography (PET) Molecular Imaging in Understanding Metabolic Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 October 2020) | Viewed by 5562
Special Issue Editors
Interests: beta cell mass; drug development; inflammation; medical imaging; metabolic disease; molecular imaging; neuroendocrine tumors; positron emission tomography (PET); radiopharmaceuticals; translational studies
Interests: type 1 diabetes; beta-cell physiology; translational medicine; cellular therapies; beta-cell imaging; positron emission tomography (PET)
Interests: PET radiochemistry; preclinical PET; clinical PET; tracer development; inflammation and fibrosis
Special Issue Information
Dear Colleagues,
In recent decades, there has been significant progress in the molecular understanding of several metabolic diseases, including type 1 and type 2 diabetes. In the experimental setting, we are able to reverse both induced and spontaneously developed diabetes in several animal models. However, a cure for human diabetes still eludes us, presumably due to critical discrepancies between the molecular basis of metabolic disease in humans as compared to our animal models. Non-invasive molecular imaging techniques, e.g., positron emission tomography (PET), offer a potential solution to improve the understanding of the etiology of metabolic disease by enabling direct and longitudinal in vivo studies of critical molecular processes involved, e.g., hormone receptors, insulin resistance, beta cell mass and physiology, etc. The field of molecular imaging has been revolutionized during the last 20 years, but so far, this has not been fully utilized in the study of diabetes. This Special Issue focuses on recent progress in understanding the molecular basis of metabolic disease utilizing PET.
We welcome original research and review articles on metabolic disease in the field of molecular imaging.
Prof. Gunnar Antoni
Dr. Daniel Espes
Dr. Olof Eriksson
Guest Editors
Manuscript Submission Information
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Keywords
- Positron emission tomography (PET)
- Molecular imaging
- Beta cells
- Diabetes
- Metabolic disease
- Metabolism
- Inflammation
- Radiochemistry
- Hormone receptors
- Drug mode of action