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Special Issue "Lipid as a Cancer Therapeutic Target"
Deadline for manuscript submissions: 31 March 2020.
Interests: lipid metabolism; nuclear lipids; cancer; cell proliferation and differentiation; neurodegenerative disorders; liver; brain; thyroid
Interests: Pharmacology, Lipids, Prostaglandins, Sphingolipids, Cancer; Colon, Inflammation
Interests: sphingolipid and prostaglandin signalling in health and disease
Lipids are not only components of cellular membranes but also constitute important signaling molecules. They can influence cellular signaling pathways via binding to extracellular cellular receptors or intracellular molecules, like phosphatases and kinases. Additionally, they can form special membrane domains, which represent important signaling platforms for the activation of membrane-associated proteins. With regard to these multiple cellular functions, lipids are important players in physiological and pathophysiological processes and interesting targets for mostly incurable diseases like cancer. Prostaglandin E2 (PGE2) and sphingosine-1 phosphate (S1P) are well-known lipids that promote cancer growth. However, other lipids are also deregulated in cancer and interfering with the synthesis or binding of these lipids are promising approaches for cancer therapy. This Special Issue will summarize current knowledge of therapeutics that target lipids as a new treatment option for cancer therapy. We invite researchers in the broad field of sphingolipids, cholesterol, prostaglandins, leukotrienes, and phospholipids to contribute to this Special Issue.
Prof. Dr. Andrea Huwiler
Prof. Dr. Elisabetta Albi
Dr. Sabine Groesch
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- lipid targets
- lipid metabolism
- lipid signaling
- lipid cancer therapy