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Special Issue "Molecular Advances in Hypertension"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 June 2019).
Assoc. Prof. Cristiano Fava Website E-Mail
Department of Medicine, University of Verona, Verona, Italy
Interests: hypertension; cardiovascular risk factors; genetics; fatty acids; epoxyeicosatrienoic acids; antiangiogenic factors; arterial stiffness; oxidative stress; endothelium; fatty liver; obstructive sleep apnoea; nutrition; renovascular disease; metabolic syndrome; pre-eclampsia; platelets; thrombosis
Constantly elevated blood pressure (arterial hypertension) is the most prevalent risk factor for cardiovascular disease, which every year leads to millions of deaths and disability worldwide, especially due to coronary artery disease and stroke. Blood pressure is a paradigmatic example of a complex trait and consequently hypertension is a clear model of multifactorial disease, since many risk factors contribute to its pathogenesis. Thus, molecular aspects regarding extremely different determinants of blood pressure homeostasis could play a role in its pathogenesis, each one with a different effect size, different behaviour, different interactions, and all these aspects may be differently expressed in different individuals, that is, the same algorithm linking all the variables is not applicable to distinct individuals.
This Special Issue will cover at least some of the many “molecular advances in hypertension”, exploring possible influences of genetics and epigenetics components, nutrients, including fatty acids and electrolyte intake, hormonal systems such as the renin angiotensin aldosterone system, the natriuretic peptide network, autonomic nervous system, epoxyeicosatrienoic acids, adipokines, then angiogenic and antiangiogenic factors, and finally the master role of the ageing vascular tree, oxidative stress, the endothelium and the kidney. Even other, less-explored adjuvants of high blood pressure will be included, such as the immune system, the microbiome and the fatty liver.
Assoc. Prof. Cristiano Fava
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- fatty acids
- renin angiotensin aldosterone system
- the natriuretic peptides
- autonomic nervous systems
- epoxyeicosatrienoic acids
- antiangiogenic factors
- arterial stiffness
- immune system
- fatty liver