Special Issue "Cytoplasmic Sensors: Infection, Inflammation, and Immunity"
Deadline for manuscript submissions: closed (31 May 2019).
Cytoplasmic sensors play sentinel roles in detecting intracellular pathogen- or self-derived molecular patterns and initiate a proper healing-immune response. While important for protecting us from invading pathogens and dangers, dysregulated cytoplasmic sensors can promote autoinflammatory disorders. In addition to initiating signalling cascade that results in the production of pro-inflammatory cytokines and antimicrobial peptides, some members of the cytoplasmic sensors (e.g., NLRP1b, NLRP3, NLRC4, AIM2, and PYRIN) assemble a multimeric protein complex known as inflammasomes. The last decade has seen an unprecedented development in our understanding of how these cytoplasmic sensors function within our cells to not only provide immunity but also maintain cellular homeostasis. Manuscripts (articles and reviews) relating to the recent advancement in our understanding of the cellular, molecular, and biochemical pathways that are regulated by cytoplasmic sensors will be given priority and considered for this Special Issue.
Dr. Prajwal Gurung
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- pathogen-recognition receptors
- cytoplasmic sensors
- nod-like receptors