Special Issue "Membrane Protein Based Biosensors"
Deadline for manuscript submissions: closed (31 July 2015).
Interests: biomimetics; self-assembly; functional supported lipid membranes; cell envelope structures of archaea; bioinspired materials; biosensors; nanobiotechnology; smart nanocarriers for drug targeting and drug delivery
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Special Issue in International Journal of Molecular Sciences: Membrane Protein Based Biosensors 2016
This Special Issue is dedicated to past and future developments in the field of biosensors whose receptive elements comprise either of (modified) membrane-active peptides, or of native or genetically engineered membrane-associated, as well as (trans)membrane proteins. The design of smart lipid membrane platforms is crucial for the functioning of membrane-active peptides and proteins, and can either be implemented by liposomal architectures, free-standing lipid bilayers, or planar lipid membranes attached to porous or solid supports. The single-molecule selectivity and specificity of the binding process, together with the expected intrinsic gain factor obtained when utilizing flow through a channel, pore or receptor have attracted the attention of scientists working in multidisciplinary fields. However, for the development of implementable biosensors, lab-on-a-chip and microfluidic devices challenging technical problems such as the fabrication of stable lipid membranes, the incorporation of a functional enzyme or receptor into these architectures, and the marriage of the modified membrane to a physical transducer need to be solved. Recently critical endeavours and new discoveries in this scientific field have been achieved and thus, highly sensitive membrane protein-based biosensors are having an increasing impact on drug screening, modern medical care and diagnostics, food safety, environmental monitoring, and biowarfare control.
Prof. Dr. Bernhard Schuster
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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- bioinspired materials
- biosensing platforms
- cell-based biosensor
- functional supported lipid membranes
- liposomes and proteoliposomes
- membrane protein-based biosensors
- membrane-active peptides
- pharmaceutical screening
- (trans)membrane proteins