Epigenetics and RNA Processing Involved in Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 36
Special Issue Editor
Interests: RNA processing; RNA transport; RNA diseases; hypoxia; epigenetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In higher eukaryotes, a vast variety of RNAs is transcribed from genome DNAs. The transcribed RNAs are subjected to RNA processing steps to produce mRNAs and non-coding RNAs. There are accumulating lines of evidence that the epigenetic modifications in DNAs, histones, and RNAs regulate RNA processing steps. In addition, the defects in RNA processing steps and epigenetic regulation often result in diseases in humans. However, the whole picture of the interplay and molecular mechanisms for these two steps and the disease onset remains to be elucidated.
As an editor of the research topic ‘Epigenetics and RNA Processing Involved in Disease’, I expect the submission from the researchers working on both RNA processing and epigenetics to connect these two fundamental but important regulatory steps in gene expression. The highlight of this topic is not restricted to the basic research for molecular mechanisms. Research for clinical and translational approaches toward the therapies for diseases caused by misregulation in epigenetics and RNA processing is also very welcome.
Dr. Naoyuki Kataoka
Guest Editor
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Keywords
- RNA processing
- RNA splicing
- epigenetics
- DNA modification
- histone modification
- RNA modification
- RNA diseases
- genetic diseases
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