Special Issue "Bioinformatics of Unusual DNA and RNA Structures"
Deadline for manuscript submissions: 31 March 2022.
Interests: G-quadruplexes; triplexes; Z-DNA/RNA; DNA cruciforms; i-motifs; bioinformatics; biophysical methods
Interests: relationship between DNA structure and function; interaction of proteins with DNA, local DNA structures and DNA damage; p53 protein and carcinogenesis; bioinformatics; immunology; neurosciences; neurodegeneration
Special Issues, Collections and Topics in MDPI journals
It is our great pleasure to open this Special Issue focused on all aspects of unusual DNA and RNA structures, mainly from the bioinformatical point of view. By unusual DNA and RNA structures, we mean primarily G-quadruplexes, i-motifs, triplexes, Z-DNA/RNA, DNA cruciforms, R-loops, RNA hairpins, etc. They are called “unusual”, but in fact, it is evident now, that they are broadly presented in the genomes of all living organisms, as well as viruses, playing important roles in the regulation of various molecular processes. Because this field of science is evolving rapidly, there is a need for integrative computational approaches allowing us to evaluate/generalize our knowledge about unusual DNA and RNA structures. The topics of this Special Issue include, but are not limited to:
- Computational analyses of DNA- and RNA-forming motifs occurring in genomes (in general)
- Comparative analyses of DNA- and RNA-forming motifs between species (from an evolutionarily point of view)
- New computational methods and tools for DNA- and RNA-forming motifs prediction and analysis
- Genome-wide association studies (GWAS) to find links between these DNA- and RNA-forming motifs and phenotypes/diseases
- Structural studies of DNA and RNA high-order structures (molecular docking, dynamics simulation, etc.)
- Screening and analyses of potential small ligands stabilizing/destabilizing DNA and RNA structures
- Interaction of proteins with unusual DNA and RNA structures
Original investigations (both full articles and short communications), as well as concise review manuscripts, from experts in the relevant research fields will be considered for publication. As guest editors, we guarantee a fair and constructive peer-review process for your submitted articles.
Dr. Petr Pečinka
Dr. Vaclav Brazda
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- ligand docking
- computational biology