Animal Models for the Study of Human Health and Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 January 2025) | Viewed by 455
Special Issue Editor
Special Issue Information
Dear Colleagues,
Animal models have played a critical role in understanding the pathogenesis and mechanisms of several diseases that are prevalent in animals and humans. They have played a critical role in developing pharmacological interventions that can treat diseases and thereby help in promoting health in animals and humans. Animal models from multiple species can be classified broadly as spontaneous models and models that are induced to imitate the signs and symptoms of diseases. Generally, whether they are spontaneous or developed, they should mimic the pathology and clinical signs of the disease that is being investigated. Although animal models have provided invaluable information related to the pathogenesis and mechanisms of disease, they sometimes fail to recapitulate complex interactions between multiple organ systems and tissues in the body. This results in difficulty comparing them for addressing specific disease conditions. This Special Issue of the International Journal of Molecular Sciences presents various animal models of human diseases of multiple organ systems and their advantages and disadvantages in using them for studying these diseases. This will be an invaluable resource for investigators who are interested in investigating specific diseases using animal models.
Prof. Dr. Puliyur S. MohanKumar
Guest Editor
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Keywords
- animal models
- rodents
- zebrafish
- drosophila
- human disease
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