The Role of Vitamin D in Human Health and Diseases, 5th Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 30 October 2025 | Viewed by 23
Special Issue Editors
Interests: nitric oxide; oxidative/nitrosative stress; in vitro bioglass compatibility; asbestos; epithelial–mesenchymal transition; oocytes competence; metabolic shift; chemoresistance
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Interests: cancer metabolism; vitamin D; TGF beta; mitochondrial metabolism; biochemistry; electromagnetic field; cancer growth; dermal wound healing; nutraceuticals
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Special Issue Information
Dear Colleagues,
The role of vitamin D in human health is so broad that we have reached the milestone of the fifth edition of this Special Issue, with aim to collect the latest evidence of the multiple effects of this hormone.
Vitamin D is a differentiative hormone that assists all tissues through its specialized functions by nuclear, non-genomic, and mitochondrial activity. In fact, vitamin D not only controls the transcription of thousands of genes but also influences cell metabolism to support specific nuclear programs. Given its broad spectrum of activity and molecular and cellular targets, it is not surprising that a deficiency in vitamin D or a defective function of its receptor can have a strong impact in many pathologies.
In the successful past editions of this Special Issue, many links with pathologies have been described and novel mechanisms of action have been revealed. Many more have yet to be discovered. This Special Issue aims to shed light on new aspects of the activity of this hormone in health and disease. Animal models, in vitro, and population studies can contribute to exciting new discoveries in pathologies such as diabetes, cancer, and autoimmune diseases, to name a few. We also welcome reviews assessing the central role of vitamin D in the physiology of healthy tissues and in the onset of disease.
This collection aims to contribute to the evolving field of vitamin D investigation, unveiling its mechanisms of action, causes of deficits, appropriate supplementation, health benefits, and clinical applications.
Dr. Loredana Bergandi
Dr. Francesca Silvagno
Guest Editors
Manuscript Submission Information
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Keywords
- vitamin D
- vitamin D receptor
- calciferol
- health
- disease
- inflammation
- gene transcription
- cell metabolism
- differentiation
- vitamin D deficiency
- vitamin D supplementation
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Related Special Issues
- The Role of Vitamin D in Human Health and Diseases 2.0 in International Journal of Molecular Sciences (18 articles)
- The Role of Vitamin D in Human Health and Diseases 3.0 in International Journal of Molecular Sciences (11 articles)
- The Role of Vitamin D in Human Health and Diseases 4.0 in International Journal of Molecular Sciences (19 articles)
- The Role of Vitamin D in Human Health and Diseases in International Journal of Molecular Sciences (11 articles)
