Developmental Biology: Computational and Experimental Approaches, 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 798
Special Issue Editor
Interests: DNA sequence analysis; mutation; single-nucleotide polymorphism (SNP); quantitative sequence-activity relationships; DNA-protein affinity; TATA-binding protein binding site (TATA box); genome-wide prediction in silico; experimental verification; in vitro; in vivo; hereditary disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Developmental biology investigates ontogenesis, which is how a single cell eventually becomes a multicellular organism, with its particular shape, dimensions, structure, life cycle, and potential to produce the next generation. At the molecular level, the mechanisms associated with signal transduction, gene replication, translation, and regulation are basic to ontogenesis. This Special Issue, entitled “Developmental Biology: Computational and Experimental Approaches” includes 14 articles on human, animal, and plant gene expression during embryogenesis, prepuberty, and ageing under normal conditions and with mutations, exposure to stresses, infections, etc. These articles appeared in the International Journal of Molecular Sciences from 2022 to 2024. According to a recent finding by Zhimulev and colleagues, any eukaryotic genome has two distinct types of genetic organization within it, each with its specific replication timing, DNA replication origins, chromatin packaging levels, composition of regulatory proteins, and particulars of the genes—specificity, the organization of their promoters, and the lengths of their introns. The differences in these attributes differentiate the housekeeping genes from most of the rest, which are called "developmental". Can the genes' neighborhood give us a clue as to which is which? Find out with this Special Issue of Developmental Biology: Computational and Experimental Approaches, 2nd Edition.
Dr. Mikhail P. Ponomarenko
Guest Editor
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Keywords
- animal
- plant
- fungus
- biological organization hierarchy
- evolutionary limitations
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