New Amphiphilic Molecules for Biomedical Applications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (20 April 2024) | Viewed by 2224
Special Issue Editor
Interests: dendrimers; polymers; peptides; molecular dynamics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Amphiphilic natural and synthetic polymers play an important role in the functioning of living organisms, are widely used in nanomedicine, for example, for the delivery of drugs, and have also proven themselves in many industrial applications. This term has traditionally been used for the amphiphilic interactions of biomacromolecules and polymers with the most common solvent, water. Natural or synthetic amphiphilic copolymers have both hydrophobic and hydrophilic parts. Block-, graft-copolymers, dendrimers, dendrigrafts, and hyperbranched amphiphilic polymers have been designed. Amphiphilic surfactants have been used in dispersion and emulsion polymerization and as the compatibilization of immiscible polymers. With the use of an increasing number of solvents, in addition to hydrophilic and hydrophobic polymers and biopolymers, the more general terms solvophilic and solvophobic polymers began to be widely used, referring to the solubility of these molecules in other solvents, as well as the concept of polyphilic and, in particular, triphilic interactions and polymers, including additional interactions such as fluorophilicity.
As is known, amphiphilic and polyphilic molecules can self-organize in solution into various spatial structures from simple spherical or cylindrical micelles and vesicles to more complex multicompartment structures. These structures can be used to deliver drugs and genetic material to target cells.
The purpose of this Special Issue is to attract works devoted to a wide range of issues related to amphiphilic and polyphilic linear and branched macromolecules, ranging from their synthesis and characterization to theoretical studies and mathematical modeling, as well as the use of these systems in biomedical and industrial applications.
Prof. Dr. Igor Neelov
Guest Editor
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Keywords
- amphiphilic polymers and biopolymers
- macromolecules of complex topology
- self-assembling
- synthesis
- characterization
- computer simulation
- drug and gene delivery
- nanomedicine
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