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Molecular Mechanisms of Myocardial Injury and Ventricular Dysfunction: Pathways and Therapeutic Targets

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 30 December 2025 | Viewed by 53

Special Issue Editor


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Guest Editor
Department of Medicine, University of Murcia, 30120 Murcia, Spain
Interests: myocardial infarction; adverse remodeling; heart failure; cardiotoxicity; cardiac dysfunction; ventricular remodeling; cardioprotection; ischemic heart disease; cardiomyopathy; cardiac regeneration
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to gather the latest research focusing on the molecular and cellular mechanisms underlying myocardial injury and ventricular dysfunction. The objectives include:

To elucidate key signaling pathways involved in cardiac injury and remodeling, such as oxidative stress, inflammation, apoptosis, and fibrosis;  To explore novel molecular targets and biomarkers for early diagnosis and prognosis of ventricular dysfunction; To highlight advances in pharmacological and genetic interventions that mitigate myocardial damage and improve cardiac function; To foster interdisciplinary approaches integrating molecular biology, pharmacology, and clinical insights to better understand cardiac pathophysiology.

We welcome original research articles, comprehensive reviews, and translational studies that deepen understanding of myocardial injury at the molecular level and its impact on ventricular function. Contributions investigating new therapeutic strategies, including drug development, gene therapy, and molecular modulators, are especially encouraged.

Dr. Antonio Lax
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • myocardial injury
  • ventricular dysfunction
  • drug development
  • gene therapy
  • molecular modulators

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Published Papers

This special issue is now open for submission.
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