Advanced Research in Immunotoxicity and Oxidative Stress
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 1343
Special Issue Editor
Interests: nanoparticles; food toxicants; toxicity; toxicokinetics; mechanism; interactions
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Concerns about toxicity related to macrophage activation and immune systems are currently increasing, potentially due to foods, food additives, nanomaterials, toxicants, natural compounds, and functional ingredients. Macrophages play a role in the immune response and are primary targets in many diseases. M1 macrophage activation leads to the production of pro-inflammatory cytokines, phagocytosis of microbes, and initiation of an immune response, while M2 macrophages promote wound healing, anti-inflammatory responses, and tissue repair. Maintaining a balance between pro- and anti-inflammatory activation is essential for normal immunologic function. Meanwhile, inflammation can be triggered by oxidative stress, which causes a range of chronic diseases.
This Special Issue will focus on toxicity associated with macrophage activation, including pro- and anti-inflammatory responses in diseases, toxicity, health, and the immune system. Studies on oxidative-stress-induced inflammation and related diseases are also encouraged. We welcome studies involving in vitro cell lines, in vivo animal models, mechanisms, and signaling pathways. Research works focusing on the benefical aspects of functional foods or natural ingredients are also welcome.
Prof. Dr. Soo-Jin Choi
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- toxicity
- macrophage activation
- pro-inflammation
- anti-inflammation
- oxidative stress
- foods
- food additives
- nanomaterials
- toxicants
- natural compounds
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