Circulating Biomarkers for the Diagnosis of Neurobiological Diseases 2.0

Dear Colleagues,

Neurobiological diseases represent a major health problem. Even before COVID-19, they were the second leading cause of death and the leading cause of disability all over the world. Since the beginning of the pandemic, the rise in many neurobiological symptoms and the aggravation of current neurobiological conditions, particularly in the elderly, due to COVID-19 have been observed. As of now, many people are suffering due to a condition called long COVID-19, which has deteriorating effects on neurobiological systems in particular.

The above being the case, newer and more precise methods are needed for the diagnosis and classification of the stages of neurobiological diseases. Recently, scientific research has focused on novel circulating biomarkers, which are biological indicators that objectively measure and evaluate physiological and/or pathophysiological parameters or pharmacological responses to therapeutics.

Current research on circulating microRNAs (miRNAs) have suggested that they play a crucial role in regulating gene expression, and they have become an intensely studied research topic because of their close connection with the development of neurobiological diseases. Circulating miRNAs are believed to be potential biomarkers for various neurobiological diseases due to their valuable characteristics, including their sustentation, reliability, and high abundance in body fluids.

In this Special Issue, we focus on circulating biomarkers for the diagnosis and reliable detection of the different stages of neurobiological diseases, their diverseness, and their pathogenesis, thereby designing targeted tailored treatments and predicting response outcomes to interventions.

Dr. Yasemin M. Akay
Guest Editor

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