The Roles of Ion Channels and Transporters in Intracellular Signaling

Dear Colleagues,

Ion channels and transporters, found in all cells, are transmembrane proteins that enable the passive flow of ions both in and out of cells or cellular organelles, following their electrochemical gradients. Proper maintenance of ion channels and transporters is critical for a range of cellular processes, such as signal transduction, neurotransmitter release, nerve impulses, muscle contraction, hormone secretion, volume regulation, growth, motility, apoptosis, and ion and water homeostasis. Dysfunction of ion channels or transporters may result in diseases of the nervous system (e.g., epilepsy), the cardiovascular system (e.g., Brugada syndrome), the respiratory system (e.g., cystic fibrosis), the endocrine system (e.g., neonatal diabetes mellitus), the urinary system (e.g., Bartter syndrome), and the immune system (e.g., Isaac syndrome).

This Special Issue welcomes the submission of original research and review articles that shed light on the importance of ion channels or transporters and the signaling pathways involved in the pathophysiology of human diseases and suggest new strategies for treatment.

Dr. Jinwei Zhang
Dr. Zhen Wang
Prof. Dr. Zhengqiu Li
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.