Special Issue "Bone Development and Growth"
Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 8422
Interests: cartilage; growth plate; chondrogenic differentiation; osteogenic differentiation; bone biology
Special Issues, Collections and Topics in MDPI journals
The skeleton is a structure of elements of various shapes and origins that supports and protects the body. The development and growth of the skeleton is an ongoing, life-long process. Skeletal elements, or bones, are mainly formed by cartilage and osseous tissue. Each has a specific cell type — chondrocytes in cartilage and osteoblasts and osteoclasts in osseous tissue — with its own differentiation pathway. There have been many recent significant conceptual advances in our understanding of bone development, but the mechanisms involved are so complex that researchers have only just begun to understand them and they have not yet been fully illustrated. The aim of this Special Issue is to present an up-to-date perspective on the process of formation and maintenance of the skeleton. On this basis, this Special Issue focuses on bone development and growth, including the mechanisms of bone formation, pathways that regulate the differentiation of cartilage cells (chondrocytes), bone-forming cells (osteoblasts) and bone - destroying cells (osteoclasts), limb development, endochondral and intramembranous ossification, structural aspects of longitudinal and transverse growth of bones, the role of hormones in bone formation and microarchitecture, bone growth pathologies, heterotopic bone formation, bone repair and transplantation, and bone regenerative medicine. Thus, it is open to contributions from anyone interested in bone development and function, including anatomists, cell biologists, physiologists, biochemists, orthopedists, pathologists, clinicians and biomedical engineers.
Prof. Dr. José López
Manuscript Submission Information
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- bone development
- bone cells
- bone matrix
- intramembranous bone
- endochondral bone
- growth plate
- bone structure
- bone remodeling
- growth factors
- bone morphogenic protein
- bone metabolism markers
- fracture repair
- bone defects
- bone quality
- heterotopic bone formation
- new bone formation